Liver sinusoidal endothelial cells (LSECs) form the wall of the hepatic sinusoids. Unlike
other capillaries, they lack an organized basement membrane and have cytoplasm that is …

The liver is a central organ in the human body, coordinating several key metabolic roles. The
structure of the liver which consists of the distinctive arrangement of hepatocytes, hepatic …

Background Descriptions of the pathological features of coronavirus disease-2019 (COVID-
19) caused by the novel zoonotic pathogen severe acute respiratory syndrome coronavirus …

The pathogenesis of SARS-CoV-2 remains to be completely understood, and detailed SARS-
CoV-2 cellular cytopathic effects requires definition. We performed a comparative …

The prevalence of liver cancer is constantly rising, with increasing incidence and mortality in
Europe and the USA in recent decades. Among the different subtypes of liver cancers …

Thrombocytopenia, which signifies a low platelet count usually below 150× 109/L, is a
common finding following or during many viral infections. In clinical medicine, mild …

Liver sinusoidal endothelial cells (LSEC) form a unique barrier between the liver sinusoids
and the underlying parenchyma, and thus play a crucial role in maintaining metabolic and …

The clinical translation of messengerRNA (mRNA) drugs has been slowed by a shortage of
delivery vehicles that potently and safely shuttle mRNA into target cells. Here, we describe …

Liver sinusoidal endothelial cells (LSECs) are the gatekeeper cells in the liver, contributing
critical roles in liver physiological and pathological changes. Factors such as dietary …

The increased production of derivatives of molecular oxygen and nitrogen in the form of
reactive oxygen species (ROS) and reactive nitrogen species (RNS) lead to molecular …