Adipose Tissue in Breast Cancer Microphysiological Models to Capture Human Diversity in Preclinical Models

KM Hamel, TP Frazier, C Williams, T Duplessis… - International Journal of …, 2024 - mdpi.com
Female breast cancer accounts for 15.2% of all new cancer cases in the United States, with
a continuing increase in incidence despite efforts to discover new targeted therapies. With …

In-vitro assays for immuno-oncology drug efficacy assessment and screening for personalized cancer therapy: scopes and challenges

MM Rahman, G Wells, JK Rantala… - Expert Review of …, 2024 - Taylor & Francis
Introduction Immunotherapies have revolutionized cancer treatment, but often fail to produce
desirable therapeutic outcomes in all patients. Due to the inter-patient heterogeneity and …

Dynamic Interplay in Tumor Ecosystems: Communication between Hepatoma Cells and Fibroblasts

G Petővári, G Tóth, L Turiák, A L. Kiss… - International Journal of …, 2023 - mdpi.com
Tumors are intricate ecosystems where cancer cells and non-malignant stromal cells,
including cancer-associated fibroblasts (CAFs), engage in complex communication. In this …

[PDF][PDF] The Role of Adipose Tissue in Capturing Human Diversity in Breast Cancer Preclinical Models

K Hamel - obatalasciences.com
Female breast cancer represents 15.2% of all new cancer cases in the United States with an
estimated 297,790 new cases and 43,170 deaths in 2023 [1]. Based on data collated by the …