Pulmonary embolism: update on management and controversies

L Duffett, LA Castellucci, MA Forgie - Bmj, 2020 - bmj.com
Pulmonary embolism is a common and potentially fatal cardiovascular disorder that must be
promptly diagnosed and treated. The diagnosis, risk assessment, and management of …

Factor XI inhibition for the prevention of venous thromboembolism: an update on current evidence and future perspectives

G Poenou, T Dumitru Dumitru, L Lafaie… - Vascular Health and …, 2022 - Taylor & Francis
During the past decade, emergence of direct oral anticoagulants (DOACs) has drastically
improved the prevention of thrombosis. However, several unmet needs prevail in the field of …

[HTML][HTML] Venous thromboembolism: Recent advancement and future perspective

Y Yamashita, T Morimoto, T Kimura - Journal of Cardiology, 2022 - Elsevier
Clinicians have been more and more often encountering patients with venous
thromboembolism (VTE), including pulmonary embolism and deep vein thrombosis, leading …

Prevalence, treatment, and prognosis of tumor thrombi in renal cell carcinoma

FHJ Kaptein, T van der Hulle, SJE Braken… - Cardio Oncology, 2022 - jacc.org
Background Renal cell carcinoma (RCC) can be complicated by a venous tumor thrombus
(TT), of which the optimal management is unknown. Objectives This study sought to assess …

[HTML][HTML] Incidence and determinants of thrombotic and bleeding complications in patients with glioblastoma

FHJ Kaptein, MAM Stals, MY Kapteijn… - Journal of Thrombosis …, 2022 - Elsevier
Background Glioblastoma patients are considered to be at high risk of venous
thromboembolism (VTE) and major bleeding (MB), although reliable incidence estimates are …

[HTML][HTML] Overview of the therapeutic potential of aptamers targeting coagulation factors

M Liu, K Zaman, YM Fortenberry - International Journal of Molecular …, 2021 - mdpi.com
Aptamers are single-stranded DNA or RNA sequences that bind target molecules with high
specificity and affinity. Aptamers exhibit several notable advantages over protein-based …

Pathophysiology and optimal treatment of intracranial branch atheromatous disease

I Deguchi, S Takahashi - Journal of Atherosclerosis and Thrombosis, 2023 - jstage.jst.go.jp
Intracranial branch atheromatous disease (BAD) is a pathological condition characterized by
the occlusion of a relatively large perforating branch (700–800 µm) near the orifice of a …

The rebirth of the contact pathway: a new therapeutic target

P Srivastava, D Gailani - Current opinion in hematology, 2020 - journals.lww.com
The rebirth of the contact pathway: a new therapeutic target : Current Opinion in Hematology
The rebirth of the contact pathway: a new therapeutic target : Current Opinion in Hematology …

The journey through the pathogenesis and treatment of venous thromboembolism in inflammatory bowel diseases: a narrative review

A Boccatonda, M Balletta, S Vicari… - … in Thrombosis and …, 2023 - thieme-connect.com
Inflammatory bowel diseases (IBDs) are chronic inflammatory disorders of the
gastrointestinal tract including Crohn's disease and ulcerative colitis, which may result in …

A new strategy for anticoagulation: the factor XI inhibitors

MC Vedovati, C Becattini, G Agnelli - European Journal of Internal Medicine, 2023 - Elsevier
Direct oral anticoagulants (DOACs) are currently the first-choice therapy for the prevention of
cardioembolic events in patients with atrial fibrillation and for the treatment of venous …