Background Neurodegenerative disorders are a group of age-associated diseases
characterized by progressive degeneration of the structure and function of the CNS. Two key …

The degeneration and dysfunction of neurons are key features of neurodegenerative
diseases (NDs). Currently, one of the main challenges facing researchers and clinicians is …

INTRODUCTION The choroid plexus is a secretory epithelial tissue of the central nervous
system (CNS) responsible for cerebrospinal fluid (CSF) production and functions as a barrier …

Objective To investigate neurodegenerative and inflammatory biomarkers in people with
amyotrophic lateral sclerosis (PALS), evaluate their predictive value for ALS progression …

Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurodegenerative disease.
While genetics and other factors contribute to ALS pathogenesis, critical knowledge is still …

Inflammatory processes and proinflammatory cytokines have a key role in the cellular
processes of neurodegenerative diseases and are linked to the pathogenesis of functional …

Neurodegenerative diseases are characterised by the irreversible degeneration of neurons
in the central or peripheral nervous systems. These include amyotrophic lateral sclerosis …

Neuroinflammation plays an important role in amyotrophic lateral sclerosis (ALS)
pathogenesis. However, it is difficult to evaluate inflammation of the central nervous system …

Amyotrophic lateral sclerosis (ALS) is an incurable and fatal disorder characterized by the
progressive loss of motor neurons in the cerebral cortex, brain stem, and spinal cord …

Amyotrophic lateral sclerosis (ALS) is a rare deadly progressive neurological disease that
primarily affects the upper and lower motor neurons with an annual incidence rate of 0.6 to …