Background The identification of blood-based biomarkers specific to the diagnosis of
amyotrophic lateral sclerosis (ALS) is an active field of academic and clinical research …

The wobbler mouse is a widely used model system of amyotrophic lateral sclerosis and
exhibits progressive neurodegeneration and neuroinflammation in association with skeletal …

Abstract Introduction/Aims Biomarkers have shown promise in amyotrophic lateral sclerosis
(ALS) research, but the quest for reliable biomarkers remains active. This study evaluates …

Objective: To evaluate safety, tolerability and feasibility of long-term treatment with
Granulocyte-colony stimulating factor (G-CSF), a well-known hematopoietic stem cell factor …

The discovery, development, and validation of novel candidate biomarkers in Alzheimer's
disease (AD) and other neurodegenerative diseases (NDs) are increasingly gaining …

It is increasingly recognized that blood-spinal cord barrier (BSCB) breakdown is a hallmark
of amyotrophic lateral sclerosis (ALS). BSCB integrity is disrupted prior to disease onset …

Abstract Amyotrophic Lateral Sclerosis (ALS) belongs to the family of neurodegenerative
disorders and is classified as fronto-temporal dementia (FTD), progressive muscular …

Reticulons (RTNs) are crucial regulatory factors in the central nervous system (CNS) as well
as immune system and play pleiotropic functions. In CNS, RTNs are transmembrane …

Inflammatory signaling is thought to modulate the neurodegenerative cascade in
amyotrophic lateral sclerosis (ALS). We have previously shown that expression of Interleukin …

Резюме Боковой амиотрофический склероз (БАС)—фатальное нейродегенеративное
заболевание, не поддающееся эффективн ому лечени ю. На сегодняшний день …