Biological characteristics of the junctional epithelium

M Shimono, T Ishikawa, Y Enokiya, T Muramatsu… - …, 2003 - ieeexplore.ieee.org
This review summarizes the biological properties of the junctional epithelium, focusing on its
developmental aspects, wide intercellular spaces and desmosomes, dense granules …

Outcomes of direct oral anticoagulants in atrial fibrillation patients across different body mass index categories

AF Barakat, S Jain, A Masri, L Alkukhun… - Clinical …, 2021 - jacc.org
Objectives This study sought to evaluate direct oral anticoagulant (DOAC) outcomes (vs.
warfarin) in patients with atrial fibrillation (AF) across body mass index (BMI) categories …

[HTML][HTML] Metabolic Syndrome and Atrial Fibrillation: Different Entities or Combined Disorders

GE Zakynthinos, V Tsolaki, E Oikonomou… - Journal of Personalized …, 2023 - mdpi.com
Obesity, hypertension, insulin resistance, and dyslipidemia are all clusters of an entity called
“Metabolic Syndrome”. The global trends of this syndrome's incidence/prevalence continue …

The obesity paradox for outcomes in atrial fibrillation: Evidence from an exposure‐effect analysis of prospective studies

X Liu, L Guo, K Xiao, W Zhu, M Liu, R Wan… - Obesity …, 2020 - Wiley Online Library
The impact of obesity on the prognosis of atrial fibrillation (AF) remains controversial. We
conducted an exposure‐effect meta‐analysis of prospective studies to clarify the relationship …

Edoxaban versus warfarin in patients with atrial fibrillation at the extremes of body weight: an analysis from the ENGAGE AF-TIMI 48 trial

G Boriani, CT Ruff, JF Kuder, M Shi… - Thrombosis and …, 2021 - thieme-connect.com
Background The effects of anticoagulants at extremes of body weight (BW) are not well
described. The aim of this study was to analyze the pharmacokinetics/pharmacodynamics …

Direct oral anticoagulants in obesity: an updated literature review

J Sebaaly, D Kelley - Annals of Pharmacotherapy, 2020 - journals.sagepub.com
Objective: To review literature on the use of direct-acting oral anticoagulants (DOACs) in
patients with high body weight (BW) and/or high body mass index (BMI) and to make …

Obesity paradox and stroke outcomes according to stroke subtype: a propensity score-matched analysis

SH Lee, JM Jung, MH Park - International Journal of Obesity, 2023 - nature.com
Objective Obesity has traditionally been considered a risk factor for ischemic stroke.
However, some clinical observations have reported a complex relationship between patients …

Efficacy and Safety of Non–Vitamin-K Antagonist Oral Anticoagulants Versus Warfarin Across the Spectrum of Body Mass Index and Body Weight: An Individual …

SM Patel, E Braunwald, J Steffel, G Boriani… - Circulation, 2024 - Am Heart Assoc
BACKGROUND: The efficacy and safety of non–vitamin-K antagonist oral anticoagulants
(NOACs) across the spectrum of body mass index (BMI) and body weight (BW) remain …

Impact of obesity on atrial fibrillation pathogenesis and treatment options

R Sha, O Baines, A Hayes, K Tompkins… - Journal of the …, 2024 - Am Heart Assoc
Atrial fibrillation (AF) is the most common cardiac arrhythmia. AF increases the risk of stroke,
heart failure, dementia, and hospitalization. Obesity significantly increases AF risk, both …

Bodyweight fluctuation is associated with increased risk of incident atrial fibrillation

HJ Lee, EK Choi, KD Han, E Lee, I Moon, SR Lee… - Heart Rhythm, 2020 - Elsevier
Background Obesity and weight gain are established risk factors for atrial fibrillation (AF).
Objective The purpose of this study was to investigate whether bodyweight variability is also …