Association between body mass index and long-term clinical outcomes in patients with non-valvular atrial fibrillation taking oral anticoagulants

M Nezu, S Ueda, K Uchida, F Sakakibara, N Kinjo… - Heart and Vessels, 2023 - Springer
Background and aims The association between body mass index (BMI) and clinical
outcomes of patients with non-valvular atrial fibrillation (NVAF) taking oral anticoagulants …

Edoxaban in elderly patient with morbid obesity and atrial fibrillation: the role of plasma levels evaluation for selecting the appropriate dose

V Russo, A Rago, N Laezza, P Di Micco… - … Archives for Chest …, 2020 - monaldi-archives.org
We present the case of a 80-year-old man with atrial fibrillation, morbid obesity (weight 123
kg, height 167 cm, BMI 44.1), high clearance of creatinine and pharmacological polytherapy …

[HTML][HTML] Use of DOACs in frail elderly patients in light of class genericization

GL Botto, P Capranzano, P Colonna… - International Journal of …, 2024 - Elsevier
Background Frailty and comorbidity influence the therapeutic approach in everyday clinical
practice. The DOACs genericization opens a reflection on their differences from a …

Predictive value of nutritional indices for left atrial thrombus in patients with valvular atrial fibrillation

Y Zhou, E Liang, J Ma, X Wang, H Fu - BMC Cardiovascular Disorders, 2023 - Springer
Background The prognostic nutritional index (PNI) and geriatric nutritional risk index (GNRI)
are well known indicators for adverse outcomes in various diseases, but there is no …

Direct-Acting Oral Anticoagulants in patients at extremes of body weight: a review of pharmacological considerations and clinical implications

R Talerico, R Pola, FA Klok, MV Huisman - TH Open, 2024 - thieme-connect.com
Patients at extremes of body weight are underrepresented in randomized controlled trials of
direct-acting oral anticoagulants (DOACs). Therefore, their optimal anticoagulant treatment …

Factors associated with edoxaban concentration among patients with atrial fibrillation

SY Lin, CH Kuo, LT Ho, YB Liu, CF Huang… - Frontiers in …, 2021 - frontiersin.org
Background and Purpose: Edoxaban exposure varies across different ethnicities. The
purpose of our study was to examine the risk factors associated with high or low edoxaban …

Non-vitamin K antagonist oral anticoagulants for stroke prevention in atrial fibrillation: safety issues in the elderly

T Ajam, TL Cumpian, BL Tilkens… - Expert Review of …, 2020 - Taylor & Francis
Introduction Non-vitamin K antagonist oral anticoagulants (NOACs) are increasingly used for
stroke prevention in patients with atrial fibrillation (AF). Since NOACs are predominantly …

Apixaban in a morbid obese patient with atrial fibrillation: a clinical experience using the plasmatic drug evaluation

V Russo, A Paccone, A Rago, V Maddaloni… - Journal of Blood …, 2020 - Taylor & Francis
We present the case of a 45-year-old man with atrial fibrillation and morbid obesity (weight
128 kg, height 168 cm, BMI 45.4) who was switched from Warfarin 5 mg once daily to …

[HTML][HTML] Association between body mass index and the risk of bleeding in elderly patients with non-valvular atrial fibrillation taking dabigatran: a cohort study

MH Li, LH Hu, YR Xiong, YU Yu, W Zhou… - Journal of Geriatric …, 2020 - ncbi.nlm.nih.gov
Background Uncertainty remains regarding the association between body mass index (BMI)
and the risk of bleeding in patients with non-valvular atrial fibrillation (NVAF). We aimed to …

Effect of Platelet Inhibition by Cangrelor Among Obese Patients Undergoing Coronary Stenting: Insights From CHAMPION

BE Peterson, RA Harrington, GW Stone… - Circulation …, 2022 - Am Heart Assoc
Background: In randomized trials, cangrelor reduced periprocedural ischemic events related
to percutaneous coronary intervention without increasing GUSTO severe bleeding …