Assessing respiratory mechanics and muscle function is critical for both clinical practice and
research purposes. Several methodological developments over the past two decades have …

COPD is associated with a progressive loss of muscle mass and function. However, there is
an unmet need to define and standardise methods to estimate the prevalence of sarcopenia …

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a major transcription factor involved in
redox homeostasis and in the response induced by oxidative injury. Nrf2 is present in an …

Mesenchymal cells are an essential cell type because of their role in tissue support, their
multilineage differentiation capacities and their potential clinical applications. They play a …

Sarcopenia and osteoporosis are common musculoskeletal comorbidities of chronic
obstructive pulmonary disease (COPD) that seriously affect the quality of life and prognosis …

The awareness of the presence and consequences of sarcopenia has significantly
increased over the past decade. Sarcopenia is defined as gradual loss of muscle mass and …

Patients with chronic obstructive pulmonary disease (COPD) present with an advanced form
of age-related muscle loss or sarcopenia. Among multiple pathomechanisms of sarcopenia …

Simple Summary As we grow older, our muscles become smaller and weaker, a condition
called sarcopenia. Several lung diseases can further worsen sarcopenia. Among them …

The proportion of obese or overweight patients in COPD patients is increasing. Although
BMI, WC and other easy to measure indicators have been proven to be related to the risk of …

Rationale For the high prevalence of frail in patients with chronic obstructive pulmonary
disease (COPD), further study should explore an in-depth understanding of the relationship …