[HTML][HTML] Receptor-mediated muscle homeostasis as a target for sarcopenia therapeutics

JH Yoon, KS Kwon - Endocrinology and Metabolism, 2021 - synapse.koreamed.org
Sarcopenia is a disease characterized by age-related decline of skeletal muscle mass and
function. The molecular mechanisms of the pathophysiology of sarcopenia form a complex …

The anabolic applications of androgens in older adults with functional limitations

AK Gattu, AL Goldman, EC Guzelce, F Galbiati… - Reviews in Endocrine …, 2022 - Springer
Aging is associated with a progressive decrease in skeletal muscle mass, strength and
power and impairment of physical function. Serum testosterone concentrations in men …

IL-13-driven pulmonary emphysema leads to skeletal muscle dysfunction attenuated by endurance exercise

J Balnis, TC Korponay, CE Vincent… - Journal of Applied …, 2020 - journals.physiology.org
Patients with chronic obstructive pulmonary disease (COPD) usually develop skeletal
muscle dysfunction, which represents a major comorbidity in these patients and is strongly …

Body Composition, Physical Function and Exercise Capacity in Chronic Obstructive Pulmonary Disease

CM Todoroff, MJ Berry - COPD: Journal of Chronic Obstructive …, 2023 - Taylor & Francis
Current literature yields unequivocal results regarding the effect of body composition on
physical function in patients with chronic obstructive pulmonary disease and …

Intermolecular and dynamic investigation of the mechanism of action of reldesemtiv on fast skeletal muscle troponin complex toward the treatment of impaired muscle …

AR Issahaku, MAA Ibrahim, N Mukelabai… - The Protein …, 2023 - Springer
Muscle weakness as a secondary feature of attenuated neuronal input often leads to
disability and sometimes death in patients with neurogenic neuromuscular diseases. These …

Free Fatty Acid Impairs Myogenic Differentiation through the AMPKα-MicroRNA 206 Pathway

A Jiang, H Guo, L Zhang, X Jiang, X Zhang… - … and Cellular Biology, 2022 - Taylor & Francis
The activity of AMP-activated protein kinase α (AMPK α) is reduced in type 2 diabetes, and
type 2 diabetes is associated with muscular atrophy. To date, there is little known about the …

SDH subunit C regulates muscle oxygen consumption and fatigability in an animal model of pulmonary emphysema

J Balnis, LA Drake, CE Vincent… - American Journal of …, 2021 - atsjournals.org
Patients with pulmonary emphysema often develop locomotor muscle dysfunction, which is
independently associated with disability and higher mortality in that population. Muscle …

Endoplasmic reticulum stress and unfolded protein response in diaphragm muscle dysfunction of patients with stable chronic obstructive pulmonary disease

E Barreiro, A Salazar-Degracia… - Journal of Applied …, 2019 - journals.physiology.org
Respiratory muscle dysfunction is common in patients with chronic obstructive pulmonary
disease (COPD). Chronic contractile activity induces endoplasmic reticulum (ER) stress and …

Effect on muscle strength after blood flow restriction resistance exercise in early in-patient rehabilitation of post-chronic obstructive pulmonary disease acute …

CW Lau, SY Leung, SH Wah, CW Yip… - Chronic Respiratory …, 2023 - journals.sagepub.com
Background Early commencement of rehabilitation might counteract the loss of muscle
strength due to a chronic obstructive pulmonary disease acute exacerbation (COPDAE) …

[HTML][HTML] Clinical significance of pectoralis muscle strength in elderly patients with idiopathic pulmonary fibrosis

H Durdu, SU Yurdalan, I Ozmen - Sarcoidosis, Vasculitis, and …, 2022 - ncbi.nlm.nih.gov
Objective: The aims of the present study were to evaluate pectoralis muscle strength located
on the chest wall and to investigate the relationship of spirometric measurements and …