[HTML][HTML] Partial volume correction in arterial spin labeling perfusion MRI: A method to disentangle anatomy from physiology or an analysis step too far?
The mismatch in the spatial resolution of Arterial Spin Labeling (ASL) MRI perfusion images
and the anatomy of functionally distinct tissues in the brain leads to a partial volume effect …
and the anatomy of functionally distinct tissues in the brain leads to a partial volume effect …
Analysis strategies for high-resolution UHF-fMRI data
Functional MRI (fMRI) benefits from both increased sensitivity and specificity with increasing
magnetic field strength, making it a key application for Ultra-High Field (UHF) MRI scanners …
magnetic field strength, making it a key application for Ultra-High Field (UHF) MRI scanners …
The cortical origin and initial spread of medial temporal tauopathy in Alzheimer's disease assessed with positron emission tomography
Advances in molecular positron emission tomography (PET) have enabled anatomic
tracking of brain pathology in longitudinal studies of normal aging and dementia, including …
tracking of brain pathology in longitudinal studies of normal aging and dementia, including …
A high-resolution in vivo atlas of the human brain's serotonin system
The serotonin (5-hydroxytryptamine, 5-HT) system modulates many important brain
functions and is critically involved in many neuropsychiatric disorders. Here, we present a …
functions and is critically involved in many neuropsychiatric disorders. Here, we present a …
The impact of amyloid‐beta and tau on prospective cognitive decline in older individuals
Objectives Amyloid‐beta (Aβ) and tau pathologies are commonly observed among clinically
normal older individuals at postmortem and can now be detected with in vivo neuroimaging …
normal older individuals at postmortem and can now be detected with in vivo neuroimaging …
Phases of hyperconnectivity and hypoconnectivity in the default mode and salience networks track with amyloid and tau in clinically normal individuals
AP Schultz, JP Chhatwal, T Hedden… - Journal of …, 2017 - Soc Neuroscience
Alzheimer9s disease (AD) is characterized by two hallmark molecular pathologies: amyloid
aβ 1–42 and Tau neurofibrillary tangles. To date, studies of functional connectivity MRI …
aβ 1–42 and Tau neurofibrillary tangles. To date, studies of functional connectivity MRI …
Tau positron emission tomographic imaging in the Lewy body diseases
SN Gomperts, JJ Locascio, SJ Makaretz… - JAMA …, 2016 - jamanetwork.com
Importance The causes of cognitive impairment in dementia with Lewy bodies (DLB) and
Parkinson disease (PD) are multifactorial. Tau pathologic changes are commonly observed …
Parkinson disease (PD) are multifactorial. Tau pathologic changes are commonly observed …
Sex mediates relationships between regional tau pathology and cognitive decline
Objective The goal of this study was to examine sex differences in tau distribution across the
brain of older adults, using positron emission tomography (PET), and investigate how these …
brain of older adults, using positron emission tomography (PET), and investigate how these …
[HTML][HTML] Locus coeruleus integrity is related to tau burden and memory loss in autosomal-dominant Alzheimer's disease
Abnormally phosphorylated tau, an indicator of Alzheimer's disease, accumulates in the first
decades of life in the locus coeruleus (LC), the brain's main noradrenaline supply. However …
decades of life in the locus coeruleus (LC), the brain's main noradrenaline supply. However …
Blood–brain barrier opening of the default mode network in Alzheimer's disease with magnetic resonance-guided focused ultrasound
The blood–brain barrier (BBB) protects the brain but is also an important obstacle for the
effective delivery of therapeutics in Alzheimer's disease and other neurodegenerative …
effective delivery of therapeutics in Alzheimer's disease and other neurodegenerative …