RNA-binding proteins (RBPs) can regulate gene expression through post-transcriptionally
influencing all manner of RNA biology, including alternative splicing (AS), polyadenylation …

Therapy resistance remains a huge challenge for current breast cancer treatments.
Exploring molecular mechanisms of therapy resistance might provide therapeutic targets for …

Y box binding protein 1 (YB-1) is a protein with a highly conserved cold shock domain (CSD)
that also belongs to the family of DNA-and RNA-binding proteins. YB-1 is present in both the …

In heterogeneous head and neck cancer (HNC), subtype-specific treatment regimens are
currently missing. An integrated analysis of patient HNC subtypes using single-cell …

Pleural mesothelioma (PM) is characterized by poor prognosis and limited therapeutic
options. Y-box-binding protein 1 (YB-1) was shown to drive growth and migration of PM …

Background Multiple myeloma (MM) is a hematological malignancy characterized by clonal
proliferation of malignant plasma cells. Despite extensive research, molecular mechanisms …

Simple Summary Circular RNA (circRNA) have a role in carcinogenesis in different cancers,
also in hepatocellular carcinoma (HCC). The transcriptome analyses of HCC tumours …

Pancreatic ductal adenocarcinoma (PDAC) is the most aggressive digestive malignancy due
to frequent late-stage diagnosis, rapid progression and resistance to therapy. With …

Background Increasing evidence shows that liver-specific long non-coding RNAs (lncRNAs)
play important roles in the development of hepatocellular carcinoma (HCC). We identified a …

Osteosarcoma is the most common primary malignant bone tumor with a strong tendency to
metastasize, limiting the prognosis of affected patients. Genomic, epigenomic and …