The bioinorganic chemistry of mammalian metallothioneins

A Krezel, W Maret - Chemical reviews, 2021 - ACS Publications
The functions, purposes, and roles of metallothioneins have been the subject of
speculations since the discovery of the protein over 60 years ago. This article guides …

Dietary and physiological effects of zinc on the immune system

I Wessels, HJ Fischer, L Rink - Annual review of nutrition, 2021 - annualreviews.org
Evidence for the importance of zinc for all immune cells and for mounting an efficient and
balanced immune response to various environmental stressors has been accumulating in …

Micronutrients

I Cakmak, P Brown, JM Colmenero-Flores… - … mineral nutrition of …, 2023 - Elsevier
The functions of iron, manganese, copper, zinc, nickel, molybdenum, boron, and chlorine in
plants are discussed. Iron (Fe) plays a crucial role in redox systems in cells and various …

Structural basis and regulation of the reductive stress response

AG Manford, EL Mena, KY Shih, CL Gee, R McMinimy… - Cell, 2021 - cell.com
Although oxidative phosphorylation is best known for producing ATP, it also yields reactive
oxygen species (ROS) as invariant byproducts. Depletion of ROS below their physiological …

[HTML][HTML] Tinjauan literatur: bioakumulasi logam berat pada ikan di perairan indonesia

SA Akbar, HK Rahayu - Lantanida Journal, 2023 - jurnal.ar-raniry.ac.id
Heavy metals are frequently employed in a variety of industries, including industry,
agriculture, food processing, and domestic appliances. Heavy metal concentrations will be …

An integrated mass spectrometry and molecular dynamics simulations approach reveals the spatial organization impact of metal-binding sites on the stability of metal …

MD Peris-Díaz, R Guran, C Domene… - Journal of the …, 2021 - ACS Publications
Mammalian metallothioneins (MTs) are a group of cysteine-rich proteins that bind metal ions
in two α-and β-domains and represent a major cellular Zn (II)/Cu (I) buffering system in the …

The cell biology of zinc

S Clemens - Journal of Experimental Botany, 2022 - academic.oup.com
Nearly 10% of all plant proteins belong to the zinc (Zn) proteome. They require Zn either for
catalysis or as a structural element. Most of the protein-bound Zn in eukaryotic cells is found …

Zinc homeostasis governed by Golgi-resident ZnT family members regulates ERp44-mediated proteostasis at the ER-Golgi interface

Y Amagai, M Yamada, T Kowada, T Watanabe… - Nature …, 2023 - nature.com
Many secretory enzymes acquire essential zinc ions (Zn2+) in the Golgi complex. ERp44, a
chaperone operating in the early secretory pathway, also binds Zn2+ to regulate its client …

The molecular basis for zinc bioavailability

AG Hall, JC King - International journal of molecular sciences, 2023 - mdpi.com
Zinc is an essential micronutrient, and its deficiency is perhaps the most prevalent and least
understood worldwide. Recent advances have expanded the understanding of zinc's unique …

Differentiated Zn (II) binding affinities in animal, plant, and bacterial metallothioneins define their zinc buffering capacity at physiological pZn

K Mosna, K Jurczak, A Krężel - Metallomics, 2023 - academic.oup.com
Abstract Metallothioneins (MTs) are small, Cys-rich proteins present in various but not all
organisms, from bacteria to humans. They participate in zinc and copper metabolism, toxic …