[HTML][HTML] The applications of radiomics in precision diagnosis and treatment of oncology: opportunities and challenges

Z Liu, S Wang, D Dong, J Wei, C Fang, X Zhou… - Theranostics, 2019 - ncbi.nlm.nih.gov
Medical imaging can assess the tumor and its environment in their entirety, which makes it
suitable for monitoring the temporal and spatial characteristics of the tumor. Progress in …

International consensus recommendations on key outcome measures for organ preservation after (chemo) radiotherapy in patients with rectal cancer

E Fokas, A Appelt, R Glynne-Jones, G Beets… - Nature Reviews …, 2021 - nature.com
Multimodal treatment strategies for patients with rectal cancer are increasingly including the
possibility of organ preservation, through nonoperative management or local excision …

Rectal cancer, version 2.2022, NCCN clinical practice guidelines in oncology

AB Benson, AP Venook, MM Al-Hawary, N Azad… - Journal of the National …, 2022 - jnccn.org
This selection from the NCCN Guidelines for Rectal Cancer focuses on management of
malignant polyps and resectable nonmetastatic rectal cancer because important updates …

Development and validation of a radiopathomics model to predict pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal …

L Feng, Z Liu, C Li, Z Li, X Lou, L Shao… - The Lancet Digital …, 2022 - thelancet.com
Background Accurate prediction of tumour response to neoadjuvant chemoradiotherapy
enables personalised perioperative therapy for locally advanced rectal cancer. We aimed to …

MRI radiomics model predicts pathologic complete response of rectal cancer following chemoradiotherapy

J Shin, N Seo, SE Baek, NH Son, JS Lim, NK Kim… - Radiology, 2022 - pubs.rsna.org
Background Preoperative assessment of pathologic complete response (pCR) in locally
advanced rectal cancer (LARC) after neoadjuvant chemoradiotherapy (nCRT) is …

A rectal cancer organoid platform to study individual responses to chemoradiation

K Ganesh, C Wu, KP O'Rourke, BC Szeglin, Y Zheng… - Nature medicine, 2019 - nature.com
Rectal cancer (RC) is a challenging disease to treat that requires chemotherapy, radiation
and surgery to optimize outcomes for individual patients. No accurate model of RC exists to …

Assessment of a watch-and-wait strategy for rectal cancer in patients with a complete response after neoadjuvant therapy

JJ Smith, P Strombom, OS Chow, CS Roxburgh… - JAMA …, 2019 - jamanetwork.com
Importance The watch-and-wait (WW) strategy aims to spare patients with rectal cancer
unnecessary resection. Objective To analyze the outcomes of WW among patients with …

Long-term outcomes of clinical complete responders after neoadjuvant treatment for rectal cancer in the International Watch & Wait Database (IWWD): an international …

MJM Van der Valk, DE Hilling, E Bastiaannet… - The Lancet, 2018 - thelancet.com
Background The strategy of watch and wait (W&W) in patients with rectal cancer who
achieve a complete clinical response (cCR) after neoadjuvant therapy is new and offers an …

Rectal cancer, version 2.2018, NCCN clinical practice guidelines in oncology

AB Benson, AP Venook, MM Al-Hawary… - Journal of the National …, 2018 - jnccn.org
The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Rectal Cancer
address diagnosis, staging, surgical management, perioperative treatment, management of …

Adoption of total neoadjuvant therapy for locally advanced rectal cancer

A Cercek, CSD Roxburgh, P Strombom, JJ Smith… - JAMA …, 2018 - jamanetwork.com
Importance Treatment of locally advanced rectal (LARC) cancer involves chemoradiation,
surgery, and chemotherapy. The concept of total neoadjuvant therapy (TNT), in which …