Polyphenols in metabolic diseases

A Gasmi, PK Mujawdiya, S Noor, R Lysiuk… - Molecules, 2022 - mdpi.com
Polyphenols (PPs) are a large group of phytochemicals containing phenolic rings with two or
more hydroxyl groups. They possess powerful antioxidant properties, multiple therapeutic …

Mitochondrial dysfunction, oxidative stress, and therapeutic strategies in diabetes, obesity, and cardiovascular disease

KA Cojocaru, I Luchian, A Goriuc, LM Antoci… - Antioxidants, 2023 - mdpi.com
Mitochondria are subcellular organelles involved in essential cellular functions, including
cytosolic calcium regulation, cell apoptosis, and reactive oxygen species production. They …

Antioxidant Activity in Extracts from Zingiberaceae Family: Cardamom, Turmeric, and Ginger

P Ballester, B Cerdá, R Arcusa, AM García-Muñoz… - Molecules, 2023 - mdpi.com
An increase in life expectancy leads to a greater impact of chronic non-communicable
diseases. This is even more remarkable in elder populations, to whom these become main …

Efficacy and safety of dietary polyphenol supplementation in the treatment of non-alcoholic fatty liver disease: A systematic review and meta-analysis

K Yang, J Chen, T Zhang, X Yuan, A Ge… - Frontiers in …, 2022 - frontiersin.org
Background Dietary polyphenol treatment of non-alcoholic fatty liver disease (NAFLD) is a
novel direction, and the existing clinical studies have little effective evidence for its …

Personalized nutrition in the management of female infertility: new insights on chronic low-grade inflammation

G Fabozzi, G Verdone, M Allori, D Cimadomo… - Nutrients, 2022 - mdpi.com
Increasing evidence on the significance of nutrition in reproduction is emerging from both
animal and human studies, suggesting a mutual association between nutrition and female …

Effect of curcumin on rheumatoid arthritis: a systematic review and meta-analysis

H Kou, L Huang, M Jin, Q He, R Zhang… - Frontiers in …, 2023 - frontiersin.org
Objective The aim of this study is to evaluate the effectiveness and safety of curcumin in
rheumatoid arthritis patients. Methods A computerized search from PubMed, Embase …

[HTML][HTML] SCD1 is the critical signaling hub to mediate metabolic diseases: Mechanism and the development of its inhibitors

Q Sun, X Xing, H Wang, K Wan, R Fan, C Liu… - Biomedicine & …, 2024 - Elsevier
Metabolic diseases, featured with dysregulated energy homeostasis, have become major
global health challenges. Patients with metabolic diseases have high probability to manifest …

Natural compounds as promising adjuvant agents in the treatment of gliomas

F Persano, G Gigli, S Leporatti - International Journal of Molecular …, 2022 - mdpi.com
In humans, glioblastoma is the most prevalent primary malignant brain tumor. Usually,
glioblastoma has specific characteristics, such as aggressive cell proliferation and rapid …

Molecular mechanisms of curcumin in the pathogenesis of metabolic dysfunction associated Steatotic liver disease

M Guariglia, F Saba, C Rosso, E Bugianesi - Nutrients, 2023 - mdpi.com
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a multifactorial
condition characterized by insulin resistance, oxidative stress, chronic low-grade …

Mitochondrial fission as a therapeutic target for metabolic diseases: insights into antioxidant strategies

T Yu, L Wang, L Zhang, PA Deuster - Antioxidants, 2023 - mdpi.com
Mitochondrial fission is a crucial process in maintaining metabolic homeostasis in normal
physiology and under conditions of stress. Its dysregulation has been associated with …