Chemical synthesis of saponins

Y Yang, S Laval, B Yu - Advances in carbohydrate chemistry and …, 2014 - Elsevier
Saponins are a large family of amphiphilic glycosides of steroids and triterpenes found in
plants and some marine organisms. By expressing a large diversity of structures on both …

Chemistry and anticancer activity of cardiac glycosides: A review

K Shah, S Chhabra… - Chemical Biology & Drug …, 2022 - Wiley Online Library
The objective of this review is an attempt to emphasize the development in the chemistry
and to display review of diverse therapeutic actions of cardiac glycosides. Anticancer activity …

[图书][B] Advances in carbohydrate chemistry and biochemistry

D Horton - 2012 - books.google.com
Since its inception in 1945, this serial has provided critical and integrating articles written by
research specialists that integrate industrial, analytical, and technological aspects of …

Synthesis of the diverse glycosides in traditional Chinese medicine

D Zhu, B Yu - Chinese Journal of Chemistry, 2018 - Wiley Online Library
Traditional Chinese medicine (TCM) is a huge treasure trove for the discovery and
development of modern pharmaceuticals. Indeed, numerous biologically and …

Modified bleomycin disaccharides exhibiting improved tumor cell targeting

MM Madathil, C Bhattacharya, Z Yu, R Paul… - Biochemistry, 2014 - ACS Publications
The bleomycins (BLMs) are a family of antitumor antibiotics used clinically for anticancer
chemotherapy. Their antitumor selectivity derives at least in part from their ability to target …

Synthesis of the steroidal glycoside (25R)-3β, 16β-diacetoxy-12, 22-dioxo-5α-cholestan-26-yl β-D-glucopyranoside and its anti-cancer properties on cervicouterine …

MA Fernández-Herrera, S Mohan… - European journal of …, 2010 - Elsevier
The synthesis of the new glycoside (25R)-3β, 16β-diacetoxy-12, 22-dioxo-5α-cholestan-26-
yl β-d-glucopyranoside starting from hecogenin is described. This compound showed anti …

'Click'synthesis of triazole-based spirostan saponin analogs

K Pérez-Labrada, I Brouard, C Morera, F Estévez… - Tetrahedron, 2011 - Elsevier
Novel analogs of spirostan saponins in which the glycosidic bond has been replaced by a
triazole linkage are described. For this, a direct oligosaccharide–steroid conjugation …

Chemical synthesis of saponins

Y Yang, S Laval, B Yu - Advances in carbohydrate chemistry and …, 2021 - Elsevier
Saponins are a large family of amphiphilic glycosides of steroids and triterpenes found in
plants and some marine organisms. By expressing a large diversity of structures on both …

Convergent synthesis and cytotoxic activities of 26-thio-and selenodioscin

P Chen, P Wang, N Song, M Li - Steroids, 2013 - Elsevier
Convergent block syntheses of 26-thio-and selenodioscin have been achieved by
developing the highly stereoselective 1, 2-trans glycosylations of chacotriosyl imidate …

Synthesis and cytotoxic activity of diosgenyl saponin analogues

MJ Kaskiw, ML Tassotto, J Th'ng, ZH Jiang - Bioorganic & medicinal …, 2008 - Elsevier
Diosgenyl saponins are steroidal glycosides that are often found as major components in
many traditional oriental medicines. Recently, a number of naturally occurring diosgenyl …