Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities

A Jolma, T Kivioja, J Toivonen, L Cheng, G Wei… - Genome …, 2010 - genome.cshlp.org
The genetic code—the binding specificity of all transfer-RNAs—defines how protein primary
structure is determined by DNA sequence. DNA also dictates when and where proteins are …

Widespread A-to-I RNA editing of Alu-containing mRNAs in the human transcriptome

A Athanasiadis, A Rich, S Maas - PLoS biology, 2004 - journals.plos.org
RNA editing by adenosine deamination generates RNA and protein diversity through the
posttranscriptional modification of single nucleotides in RNA sequences. Few mammalian A …

The role of resistin as a regulator of inflammation: Implications for various human pathologies

M Filková, M Haluzík, S Gay, L Šenolt - Clinical immunology, 2009 - Elsevier
Resistin was originally described as an adipocyte-secreted peptide that induced insulin
resistance in rodents. Increasing evidence indicates its important regulatory roles in various …

Protein kinase A catalytic subunit isoform PRKACA; History, function and physiology

RE Turnham, JD Scott - Gene, 2016 - Elsevier
Our appreciation of the scope and influence of second messenger signaling has its origins
in pioneering work on the cAMP-dependent protein kinase. Also called protein kinase A …

TRIM family proteins: retroviral restriction and antiviral defence

S Nisole, JP Stoye, A Saïb - Nature Reviews Microbiology, 2005 - nature.com
Members of the tripartite motif (TRIM) protein family are involved in various cellular
processes, including cell proliferation, differentiation, development, oncogenesis and …

Molecular physiology and pathophysiology of electroneutral cation-chloride cotransporters

G Gamba - Physiological reviews, 2005 - journals.physiology.org
Electroneutral cation-Cl− cotransporters compose a family of solute carriers in which cation
(Na+ or K+) movement through the plasma membrane is always accompanied by Cl− in a 1 …

Loss of a callose synthase results in salicylic acid-dependent disease resistance

MT Nishimura, M Stein, BH Hou, JP Vogel, H Edwards… - Science, 2003 - science.org
Plants attacked by pathogens rapidly deposit callose, a β-1, 3-glucan, at wound sites.
Traditionally, this deposition is thought to reinforce the cell wall and is regarded as a …

Mitogen-activated protein (MAP) kinase/MAP kinase phosphatase regulation: roles in cell growth, death, and cancer

T Boutros, E Chevet, P Metrakos - Pharmacological reviews, 2008 - ASPET
Mitogen-activated protein kinase dual-specificity phosphatase-1 (also called MKP-1,
DUSP1, ERP, CL100, HVH1, PTPN10, and 3CH134) is a member of the threonine-tyrosine …

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

DS Gerhard, L Wagner, EA Feingold… - Genome …, 2004 - europepmc.org
Abstract The National Institutes of Health's Mammalian Gene Collection (MGC) project was
designed to generate and sequence a publicly accessible cDNA resource containing a …

The extended granin family: structure, function, and biomedical implications

A Bartolomucci, R Possenti, SK Mahata… - Endocrine …, 2011 - academic.oup.com
The chromogranins (chromogranin A and chromogranin B), secretogranins (secretogranin II
and secretogranin III), and additional related proteins (7B2, NESP55, proSAAS, and VGF) …