OBJECTIVE: To summarize the available scientific evidence to support clinical decisions on
how to deal with noncompliance in glaucoma patients. CLINICAL RELEVANCE: Insufficient …

Our understanding of glaucoma has undergone dramatic changes in the past decade. The
ferment has derived from new epidemiologic information, improved diagnostic methods, and …

Objective To provide the results of the Early Manifest Glaucoma Trial, which compared the
effect of immediately lowering the intraocular pressure (IOP), vs no treatment or later …

Background Primary open-angle glaucoma (POAG) is one of the leading causes of
blindness in the United States and worldwide. Three to 6 million people in the United States …

• A detailed ocular examination, including perimetry, was conducted on 5308 black and
white subjects aged 40 years and older in a population-based prevalence survey in east …

From annual examinations of 813 ocular hypertensive eyes, the authors compared optic disc
and nerve fiber layer photographs in 2 age-matched subgroups: 37 eyes that converted to …

OBJECTIVES: The Early Manifest Glaucoma Trial (EMGT) will evaluate the effectiveness of
reducing intraocular pressure (IOP) in early, previously untreated open-angle glaucoma. Its …

Background The Ocular Hypertension Treatment Study (OHTS) seeks to evaluate the safety
and efficacy of topical ocular hypotensive medication in preventing or delaying the onset of …

OBJECTIVE: The European Glaucoma Prevention Study (EGPS) seeks to evaluate the
efficacy of reduction of intraocular pressure (IOP) by dorzolamide in preventing or delaying …

OBJECTIVE: To test the validity and generalizability of the Ocular Hypertension Treatment
Study (OHTS) prediction model for the development of primary open-angle glaucoma …