Cerebral small vessel disease (SVD) gives rise to one in five strokes worldwide and
constitutes a major source of cognitive decline in the elderly. SVD is known to occur in …

Cerebral perfusion, also referred to as cerebral blood flow (CBF), is one of the most
important parameters related to brain physiology and function. The technique of dynamic …

The non-invasive nature of arterial spin labelling (ASL) has opened a unique window into
human brain function and perfusion physiology. High spatial and temporal resolution makes …

Abstract Introduction Combined PET/MRI allows for multi-parametric imaging and reveals
one or more functional processes simultaneously along with high-resolution morphology …

This article reviews the most relevant state-of-the-art magnetic resonance (MR) techniques,
which are clinically available to investigate brain diseases. MR acquisition techniques …

Diabetic neuropathy is a chronic and often disabling condition that affects a significant
number of individuals with diabetes. Long considered a disease of the peripheral nervous …

Arterial spin labeling (ASL) techniques are MR imaging methods designed to highlight the
signal coming from arterial blood by manipulation of its magnetization. These techniques …

Low-density lipoproteins (LDLs) are a naturally occurring endogenous nanoplatform in
mammalian systems. These nanoparticles (22 nm) specifically transport cholesterol to cells …

Hypoxia plays a central role in tumor stem cell genesis and is related to a more malignant
tumor phenotype, therapy resistance (eg in anti-angiogenic therapies) and radio …

Purpose: To investigate the within and between subject variability of quantitative cerebral
blood flow (CBF) measurements in normal subjects using various MRI techniques and …