[HTML][HTML] Gastrinoma

RT Jensen, T Ito - Endotext [Internet], 2023 - ncbi.nlm.nih.gov
Gastrinomas are neuroendocrine neoplasms (NENs), that occur primarily in the duodenum
and pancreas, which ectopically secrete gastrin, resulting in the Zollinger-Ellison syndrome …

Therapeutic targeting of the menin–KMT2A interaction

PR Freire, JA Cutler… - Annual Review of Cancer …, 2024 - annualreviews.org
The direct targeting of chromatin-associated proteins is increasingly recognized as a
potential therapeutic strategy for the treatment of cancer. In this review, we discuss a …

Aggressive prolactinoma

A Valea, F Sandru, A Petca… - Experimental and …, 2022 - spandidos-publications.com
Aggressive prolactinoma (APRL) is a subgroup of aggressive pituitary tumors (accounting
for 10% of all hypophyseal neoplasia) which are defined by: invasion based on radiological …

An insight on functioning pancreatic neuroendocrine neoplasms

M Bevere, A Gkountakos, FM Martelli, A Scarpa… - Biomedicines, 2023 - mdpi.com
Pancreatic neuroendocrine neoplasms (PanNENs) are rare neoplasms arising from islets of
the Langerhans in the pancreas. They can be divided into two groups, based on peptide …

The Russian registry of primary hyperparathyroidism, latest update

NG Mokrysheva, AK Eremkina, AR Elfimova… - Frontiers in …, 2023 - frontiersin.org
Introduction Until recently no major epidemiological research of primary
hyperparathyroidism (PHPT) has been conducted in the Russian Federation, this led to the …

[PDF][PDF] Multiple Endocrine Neoplasia Type 1 Syndrome Pancreatic Neuroendocrine Tumor Genotype/Phenotype: Is There Any Advance on Predicting or Preventing?

B Ramamoorthy, N Nilubol - Surgical Oncology Clinics of North America, 2023 - Elsevier
Multiple endocrine neoplasia type 1 syndrome (MEN1) is a disease caused by mutations in
the MEN1 tumor suppressor gene leading to hyperparathyroidism, pituitary adenomas, and …

Hereditary Syndromes Associated with Pancreatic and Lung Neuroendocrine Tumors

N Papadopoulou-Marketou, M Tsoli, E Chatzellis… - Cancers, 2024 - mdpi.com
Simple Summary Pancreatic neuroendocrine tumors (PanNETs) and lung NETs (LNETs)
have garnered increased attention in recent years due to their diverse clinical manifestations …

Approach of multiple endocrine neoplasia type 1 (MEN1) syndrome–related skin tumors

LC Băicoianu-Nițescu, AM Gheorghe, M Carsote… - Diagnostics, 2022 - mdpi.com
Non-endocrine findings in patients with MEN1 (multiple endocrine neoplasia) syndrome
also include skin lesions, especially tumor-type lesions. This is a narrative review of the …

Familial states of primary hyperparathyroidism: an update

F Cetani, E Dinoi, L Pierotti, E Pardi - Journal of Endocrinological …, 2024 - Springer
Background Familial primary hyperparathyroidism (PHPT) includes syndromic and non-
syndromic disorders. The former are characterized by the occurrence of PHPT in association …

Mixed-Lineage Leukaemia Gene Regulates Glucose-Sensitive Gene Expression and Insulin Secretion in Pancreatic Beta Cells

S Yoshino, E Ishida, K Horiguchi, S Matsumoto… - International Journal of …, 2024 - mdpi.com
The escalating prevalence of diabetes mellitus underscores the need for a comprehensive
understanding of pancreatic beta cell function. Interest in glucose effectiveness has …