After the protocol-related indecisive clinical trial of Oxygent, a perfluorooctylbromide/
phospholipid nanoemulsion, in cardiac surgery, that often unduly assigned the observed …

The structural complexity of the brain hinders the traditional treatment of brain diseases from
achieving desirable outcomes, which urges the research and development of multiple …

Microbubble-enhanced sonothrombolysis is a promising approach to increasing the
tolerability and efficacy of current pharmacological treatments for ischemic stroke …

Background and Purpose—The NOR-SASS (Norwegian Sonothrombolysis in Acute Stroke
Study) aimed to assess effect and safety of contrast-enhanced ultrasound treatment in an …

Background Microbubbles (MBs) combined with ultrasound sonothrombolysis (STL)
appears to be an alternative therapeutic strategy for acute ischemic stroke (IS), but clinical …

Ischemic stroke is a serious medical condition that is caused by cerebral vascular occlusion
and leads to neurological dysfunction. After stroke, patients suffer from long-term sensory …

Objectives The main objective of this study was to remove amyloid β plaques by applying
multiple sessions of focused ultrasound (US)‐induced blood‐brain barrier (BBB) opening …

Contrast ultrasound has a variety of applications in cardiovascular medicine, both in
diagnosing cardiovascular disease as well as providing prognostic information …

In recent years, the in-depth study of low-frequency sonophoresis (LFS) has greatly
elucidated its biological effects in various therapeutic applications, including drug delivery …

The urokinase-type plasminogen activator (uPA) loaded hollow nanogels (nUK) were
synthesized by a one-step reaction of glycol chitosan and aldehyde capped poly (ethylene …