[HTML][HTML] β-lactam Resistance in Pseudomonas aeruginosa: Current Status, Future Prospects
KA Glen, IL Lamont - Pathogens, 2021 - mdpi.com
Pseudomonas aeruginosa is a major opportunistic pathogen, causing a wide range of acute
and chronic infections. β-lactam antibiotics including penicillins, carbapenems …
and chronic infections. β-lactam antibiotics including penicillins, carbapenems …
Pseudomonas aeruginosa elastase (LasB) as a therapeutic target
MJ Everett, DT Davies - Drug Discovery Today, 2021 - Elsevier
The Pseudomonas aeruginosa LasB elastase (elastase B, pseudolysin) is the predominant
protease in the P. aeruginosa secretome. It has been shown to hydrolyse a vast array of host …
protease in the P. aeruginosa secretome. It has been shown to hydrolyse a vast array of host …
Facial amphiphilic naphthoic acid-derived antimicrobial polymers against multi-drug resistant gram-negative bacteria and biofilms
Inspired by the facial amphiphilic nature and antimicrobial efficacy of many antimicrobial
peptides, this work reported facial amphiphilic bicyclic naphthoic acid derivatives with …
peptides, this work reported facial amphiphilic bicyclic naphthoic acid derivatives with …
Real-time monitoring of Pseudomonas aeruginosa biofilm growth dynamics and persister cells' eradication
M Žiemytė, M Carda-Diéguez… - Emerging Microbes & …, 2021 - Taylor & Francis
Biofilm formation and the appearance of persister cells with low metabolic rates are key
factors affecting conventional treatment failure and antibiotic resistance. Using impedance …
factors affecting conventional treatment failure and antibiotic resistance. Using impedance …
Targeting multidrug-recalcitrant pseudomonas aeruginosa biofilms: combined-enzyme treatment enhances antibiotic efficacy
Y Zhang, W Wei, H Wen, Z Cheng, Z Mi… - Antimicrobial Agents …, 2023 - Am Soc Microbiol
Pseudomonas aeruginosa is an opportunistic pathogen that forms biofilms during infection,
resulting in recalcitrance to antibiotic treatment. Biofilm inhibition is a promising research …
resulting in recalcitrance to antibiotic treatment. Biofilm inhibition is a promising research …
Chemical Optimization of Selective Pseudomonas aeruginosa LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1β in Cellular and Animal …
MJ Everett, DT Davies, S Leiris, N Sprynski… - ACS Infectious …, 2023 - ACS Publications
LasB elastase is a broad-spectrum exoprotease and a key virulence factor of Pseudomonas
aeruginosa, a major pathogen causing lung damage and inflammation in acute and chronic …
aeruginosa, a major pathogen causing lung damage and inflammation in acute and chronic …
Assessment of virulence factors and antimicrobial resistance among the Pseudomonas aeruginosa strains isolated from animal meat and carcass samples
Background Pseudomonas aeruginosa bacteria are emerging causes of food spoilage and
foodborne diseases. Raw meat of animal species may consider a reservoir of P. aeruginosa …
foodborne diseases. Raw meat of animal species may consider a reservoir of P. aeruginosa …
[HTML][HTML] Inhibition of the Quorum Sensing System, Elastase Production and Biofilm Formation in Pseudomonas aeruginosa by Psammaplin A and Bisaprasin
ET Oluwabusola, NP Katermeran, WH Poh, TMB Goh… - Molecules, 2022 - mdpi.com
Natural products derived from marine sponges have exhibited bioactivity and, in some
cases, serve as potent quorum sensing inhibitory agents that prevent biofilm formation and …
cases, serve as potent quorum sensing inhibitory agents that prevent biofilm formation and …
[HTML][HTML] Genome Analysis of Pseudomonas aeruginosa Strains from Chronically Infected Patients with High Levels of Persister Formation
The appearance of persister cells with low metabolic rates are key factors leading to
antibiotic treatment failure. Such persisters are multidrug tolerant and play a key role in the …
antibiotic treatment failure. Such persisters are multidrug tolerant and play a key role in the …
Pseudomonas aeruginosa strains from both clinical and environmental origins readily adopt a stable small-colony-variant phenotype resulting from single mutations in …
ABSTRACT A subpopulation of small-colony variants (SCVs) is a frequently observed
feature of Pseudomonas aeruginosa isolates obtained from colonized cystic fibrosis lungs …
feature of Pseudomonas aeruginosa isolates obtained from colonized cystic fibrosis lungs …