In peptide vaccine therapy, a peptide with high affinity for human leukocyte antigen (HLA), is
important to stimulate the immune system to kill cancer cells. Several methods to predict …

Because of the enormous diversity of both MHC proteins and peptide epitopes,
computational epitope prediction methods are needed in order to supplement limited …

The peptide binding to Major Histocompatibility Complex (MHC) proteins is an important
step in the antigen-presentation pathway. Thus, predicting the binding potential of peptides …

Because drug discovery efforts have experienced a pronounced decline in productivity,
novel approaches to the rational design of new drugs are being introduced and developed …

Epitopes are essential peptides for immune system stimulation, such as governing helper T
lymphocyte (HTL) activation via antigen presentation and recognition. Current predictive …

Ionized groups carry net charge and thus play a major role in the electrostatic interactions
between the ligand and receptor. Therefore understanding the role of electrostatics on …

Epitopes are essential peptides for immune system stimulation, such as governing helper T
lymphocyte (HTL) activation via antigen presentation and recognition. Current predictive …

Viral pathogens often stimulate the infected host to develop an immunologic response to
viral proteins as protection against infection. Researchers have explored this human …

The present disclosure provides, in one embodiment, a method of treating or preventing an
ID2 protein-related disease in a patient at risk of developing or having such a disease by …

RESUMO O MHC é uma molécula apresentadora que possui um papel importante tanto na
apresentação de peptídeos próprios como não-próprios, para que todo o sistema imune …