Materials and Methods: We have developed a novel in silico epitope prediction method,
based on Hl. A crystal structure and a peptide docking simulation model, calculating the …

Major histocompatibility complexes (MHC) or human leukocyte antigens (HLAs) in human
are important elements of T cell-mediated immunity. They are cell surface glycoproteins …

Evolution is the uniting concept of biology and life. At its fundamental level, it operates by
sampling amino acid residues in proteins to optimize stability and function. One definition of …

Successfully incorporating backbone flexibility into the computational modeling and design
of proteins and protein interactions is a key challenge that has yet to be fully solved. Most …

T cell immune responses are driven by the recognition of peptide antigens (T cell epitopes)
that are bound to major histocompatibility complex (MHC) molecules. T cell epitope …