Inflammation is a natural protective mechanism that occurs when the body's tissue
homeostatic mechanisms are disrupted by biotic, physical, or chemical agents. The immune …

Psoriasis is one of the most widespread chronic inflammatory skin diseases, affecting about
2%–3% of the worldwide adult population. The pathogenesis of this disease is quite …

Hormetic dose responses (ie, a biphasic dose/concentration response characterized by a
low dose stimulation and a high dose inhibition) are shown herein to be commonly reported …

Psoriasis does not respond adequately to the monotherapy, tailoring combined strategies for
synergistical treatment remains challenging. We fabricated chitosan/hyaluronan nanogels to …

Psoriasis is an autoimmune disease that affects around 3–4% of the population globally
leading to skin inflammation. Tacrolimus is widely used in the treatment of psoriasis due to …

Psoriasis is an autoimmune disease mediated by disturbed T cells and other immune cells,
and is defined by deep-red, well-demarcated skin lesions. Due to its varied etiologies and …

Phytosterols have been reported to exert anti-inflammatory activity. This study aimed to
investigate the capacity of campesterol, β-sitosterol, and stigmasterol on the mitigation of …

Psoriasis is a chronic autoimmune inflammatory skin disorder characterized by epidermal
hyperplasia and aberrant immune response. In addition to aberrant cytokine production …

Abstract Background Tripterygium wilfordii Hook. f.(TwHf) belonging to the Celastraceae
family is widely used for psoriasis treatment, especially in topical therapy in Chinese …

Introduction RNA interference (RNAi) has demonstrated great potential in treating skin-
related diseases, as small interfering RNA (siRNA) can efficiently silence specific genes …