Cell–cell junctions link cells to each other in tissues, and regulate tissue homeostasis in
critical cell processes that include tissue barrier function, cell proliferation, and migration …

While gap junctions support the exchange of a number of molecules between neighboring
cells, connexin hemichannels provide communication between the cytosol and the …

Inflammation may be caused by a variety of factors and is a hallmark of a plethora of acute
and chronic diseases. The purpose of inflammation is to eliminate the initial cell injury …

Emerging evidence shows that after injury or infection, the mesenteric lymph acts as a
conduit for gut-derived toxic factors to enter the blood circulation, causing systemic …

The concept of gap junctions and their role in intercellular communication has been known
for around 50 years. Considerable progress has been made in understanding the …

Abstract Background Ischemia–reperfusion (I/R)-induced acute kidney injury (AKI) not only
prolongs the length of hospital stay, but also seriously affects the patient's survival rate …

Background/Aims: Changes in cell-to-cell communication have been linked to several
secondary complications of diabetes, but the mechanism by which connexins affect disease …

Gap junction-mediated cell-cell interactions are highly conserved and play essential roles in
cell survival, proliferation, differentiation and patterning. We report that Connexin 32 (Cx32) …

Epithelial tissue responds rapidly to environmental triggers and is constantly renewed. This
tissue is also highly accessible for therapeutic targeting. This review highlights the role of …

Dysregulation of gap junction intercellular communication (GJIC) is recognized as one of the
key hallmarks for identifying non-genotoxic carcinogens (NGTxC). Currently, there is a …