In the search of a theory of biological organisms, we propose to adopt organization as a
theoretical principle. Organization constitutes an overarching hypothesis that frames the …

Darwin introduced the concept that random variation generates new living forms. In this
paper, we elaborate on Darwin's notion of random variation to propose that biological …

We propose a conceptual and formal characterisation of biological organisation as a closure
of constraints. We first establish a distinction between two causal regimes at work in …

Biological evolution is a complex blend of ever changing structural stability, variability and
emergence of new phenotypes, niches, ecosystems. We wish to argue that the evolution of …

According to the free energy principle, life is an “inevitable and emergent property of any
(ergodic) random dynamical system at non-equilibrium steady state that possesses a …

The natural world consists of hierarchical levels of complexity that range from subatomic
particles and molecules to ecosystems and beyond. This implies that, in order to explain the …

In this book, we propose original perspectives in theoretical biology. We refer extensively to
physical methods of understanding phenomena but in an untraditional manner. At times, we …

Although the origin of self-referential consciousness is unknown, it can be argued that the
instantiation of self-reference was the commencement of the living state as phenomenal …

Organisms, be they uni-or multi-cellular, are agents capable of creating their own norms;
they are continuously harmonizing their ability to create novelty and stability, that is, they …

The principle of inertia is central to the modern scientific revolution. By postulating this
principle Galileo at once identified a pertinent physical observable (momentum) and a …