Metal-based photosensitizers as inducers of regulated cell death mechanisms
Y Zhang, BT Doan, G Gasser - Chemical Reviews, 2023 - ACS Publications
Over the last few decades, various forms of regulated cell death (RCD) have been
discovered and were found to improve cancer treatment. Although there are several reviews …
discovered and were found to improve cancer treatment. Although there are several reviews …
Immunogenic cell death inducing metal complexes for cancer therapy
L Zhang, N Montesdeoca, J Karges… - Angewandte Chemie …, 2023 - Wiley Online Library
Cancer is one of the deadliest diseases worldwide. Recent statistics have shown that
metastases and tumor relapse are the leading causes of cancer‐associated deaths. While …
metastases and tumor relapse are the leading causes of cancer‐associated deaths. While …
Synergistic reinforcing of immunogenic cell death and transforming tumor‐associated macrophages via a multifunctional cascade bioreactor for optimizing cancer …
C Huang, B Lin, C Chen, H Wang, X Lin… - Advanced …, 2022 - Wiley Online Library
Immunogenic cell death (ICD) has aroused widespread attention because it can reconstruct
a tumor microenvironment and activate antitumor immunity. This study proposes a two‐way …
a tumor microenvironment and activate antitumor immunity. This study proposes a two‐way …
Organometallic anti-tumor agents: targeting from biomolecules to dynamic bioprocesses
The great clinical success of cisplatin and its derivatives has convinced people that metal
complexes could play a more significant role in human cancer therapy. However, targeting …
complexes could play a more significant role in human cancer therapy. However, targeting …
Photodecaging of a mitochondria-localized iridium (III) endoperoxide complex for two-photon photoactivated therapy under hypoxia
Despite the clinical success of photodynamic therapy (PDT), the application of this medical
technique is intrinsically limited by the low oxygen concentrations found in cancer tumors …
technique is intrinsically limited by the low oxygen concentrations found in cancer tumors …
Ultrasound-augmented mitochondrial calcium ion overload by calcium nanomodulator to induce immunogenic cell death
P Zheng, B Ding, Z Jiang, W Xu, G Li, J Ding… - Nano letters, 2021 - ACS Publications
Immunogenic cell death (ICD), a manner of tumor cell death that can trigger antitumor
immune responses, has received extensive attention as a potential synergistic modality for …
immune responses, has received extensive attention as a potential synergistic modality for …
Golgi apparatus-targeted aggregation-induced emission luminogens for effective cancer photodynamic therapy
M Liu, Y Chen, Y Guo, H Yuan, T Cui, S Yao… - Nature …, 2022 - nature.com
Golgi apparatus (GA) oxidative stress induced by in situ reactive oxygen species (ROS)
could severely damage the morphology and function of GA, which may open up an avenue …
could severely damage the morphology and function of GA, which may open up an avenue …
Nitric oxide induces immunogenic cell death and potentiates cancer immunotherapy
Tumor cells undergoing immunogenic cell death (ICD) release immunogenic damage-
associated molecular patterns (DAMPs) to trigger a long-term protective antitumor response …
associated molecular patterns (DAMPs) to trigger a long-term protective antitumor response …
Metal-organic framework nanoagent induces cuproptosis for effective immunotherapy of malignant glioblastoma
QX Huang, JL Liang, QW Chen, XK Jin, MT Niu… - Nano Today, 2023 - Elsevier
Glioblastoma (GBM) is an aggressive brain cancer with an immunosuppressive tumor
microenvironment. Here, a copper-based nanoplatform BSO-CAT@ MOF-199@ DDM …
microenvironment. Here, a copper-based nanoplatform BSO-CAT@ MOF-199@ DDM …
Ferroptosis‐enhanced cancer immunity by a ferrocene‐appended iridium (III) Diphosphine complex
WJ Wang, YY Ling, YM Zhong, ZY Li… - Angewandte Chemie …, 2022 - Wiley Online Library
Ferroptosis is a programmed cell death pathway discovered in recent years, and ferroptosis‐
inducing agents have great potential as new antitumor candidates. Here, we report a IrIII …
inducing agents have great potential as new antitumor candidates. Here, we report a IrIII …