Acute myeloid leukemia

H Döhner, DJ Weisdorf… - New England Journal of …, 2015 - Mass Medical Soc
Acute Myeloid Leukemia | New England Journal of Medicine Skip to main content The New
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The role of allogeneic stem cell transplantation in the management of acute myeloid leukaemia: a triumph of hope and experience

J Loke, R Malladi, P Moss… - British Journal of …, 2020 - Wiley Online Library
Acute myeloid leukaemia (AML) is the commonest indication for allogeneic stem cell
transplantation (allo‐SCT) worldwide. The accumulated experience of allografting in AML …

[HTML][HTML] Indications for autologous and allogeneic hematopoietic cell transplantation: guidelines from the American Society for Blood and Marrow Transplantation

NS Majhail, SH Farnia, PA Carpenter… - Biology of Blood and …, 2015 - Elsevier
Abstract Approximately 20,000 hematopoietic cell transplantation (HCT) procedures are
performed in the United States annually. With advances in transplantation technology and …

HLA-haploidentical transplantation with regulatory and conventional T-cell adoptive immunotherapy prevents acute leukemia relapse

MF Martelli, M Di Ianni, L Ruggeri… - Blood, The Journal …, 2014 - ashpublications.org
Posttransplant relapse is still the major cause of treatment failure in high-risk acute
leukemia. Attempts to manipulate alloreactive T cells to spare normal cells while killing …

Targeting Natural Killer Cells to Acute Myeloid Leukemia In Vitro with a CD16 × 33 Bispecific Killer Cell Engager and ADAM17 Inhibition

A Wiernik, B Foley, B Zhang, MR Verneris, E Warlick… - Clinical cancer …, 2013 - AACR
Purpose: The graft versus leukemia effect by natural killer (NK) cells prevents relapse
following hematopoietic stem cell transplantation. We determined whether a novel bispecific …

T-cell-replete haploidentical HSCT with low-dose anti-T-lymphocyte globulin compared with matched sibling HSCT and unrelated HSCT

Y Luo, H Xiao, X Lai, J Shi, Y Tan, J He… - Blood, The Journal …, 2014 - ashpublications.org
We developed an approach of T-cell-replete haploidentical hematopoietic stem cell
transplantation (HSCT) with low-dose anti-T-lymphocyte globulin and prospectively …

Allogeneic hematopoietic cell transplantation for adults with acute myeloid leukemia: myths, controversies, and unknowns

V Gupta, MS Tallman… - Blood, The Journal of the …, 2011 - ashpublications.org
Progress in the last decade has improved the understanding of leukemia biology. Molecular
markers in combinations with cytogenetics have improved the risk stratification of acute …

Haploidentical hematopoietic transplantation: current status and future perspectives

Y Reisner, D Hagin, MF Martelli - Blood, The Journal of the …, 2011 - ashpublications.org
For patients with hematologic malignancies at high risk of relapse who do not have matched
donors, a suitable alternative stem cell source is the HLAhaploidentical 2 or 3-loci …

Haploidentical age-adapted myeloablative transplant and regulatory and effector T cells for acute myeloid leukemia

A Pierini, L Ruggeri, A Carotti, F Falzetti… - Blood …, 2021 - ashpublications.org
Allogeneic hematopoietic stem cell transplantation (HSCT) is the most effective treatment in
eradicating high-risk acute myeloid leukemia (AML). Here, we present data from a novel …

Reduced-intensity conditioning with combined haploidentical and cord blood transplantation results in rapid engraftment, low GVHD, and durable remissions

H Liu, ES Rich, L Godley, O Odenike… - Blood, The Journal …, 2011 - ashpublications.org
We conducted a 45 patient prospective study of reduced-intensity conditioning (RIC) and
transplantation of unrelated umbilical cord blood (UCB) and CD34+ stem cells from a …