[HTML][HTML] Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment

RA McCutcheon, RSE Keefe, PK McGuire - Molecular psychiatry, 2023 - nature.com
Cognitive deficits are a core feature of schizophrenia, account for much of the impaired
functioning associated with the disorder and are not responsive to existing treatments. In this …

Dopamine in Parkinson's disease

S Latif, M Jahangeer, DM Razia, M Ashiq, A Ghaffar… - Clinica chimica acta, 2021 - Elsevier
Parkinson's disease is a neurodegenerative disease caused by the death of neurons, ie,
cells critical to the production of dopamine, an important neurotransmitter in the brain. Here …

[HTML][HTML] Dopamine: The neuromodulator of long-term synaptic plasticity, reward and movement control

L Speranza, U Di Porzio, D Viggiano, A de Donato… - Cells, 2021 - mdpi.com
Dopamine (DA) is a key neurotransmitter involved in multiple physiological functions
including motor control, modulation of affective and emotional states, reward mechanisms …

[PDF][PDF] Imaging neurotransmitter and neuromodulator dynamics in vivo with genetically encoded indicators

BL Sabatini, L Tian - Neuron, 2020 - cell.com
The actions of neuromodulation are thought to mediate the ability of the mammalian brain to
dynamically adjust its functional state in response to changes in the environment. Altered …

Heterostructures with Built‐in Electric Fields for Long‐lasting Chemodynamic Therapy

H Zhang, Y Chen, W Hua, W Gu, H Zhuang… - Angewandte …, 2023 - Wiley Online Library
Sustained signal activation by hydroxyl radicals (⋅ OH) has great significance, especially for
tumor treatment, but remains challenging. Here, a built‐in electric field (BIEF)‐driven …

Highly Efficient Aggregation-Induced Electrochemiluminescence of Al (III)-Cbatpy Metal–Organic Gels Obtained by Ultrarapid Self-Assembly for a Biosensing …

Y Zhang, Y Chen, Y Nie, Z Yang, R Yuan… - Analytical …, 2022 - ACS Publications
Aggregation-induced electrochemiluminescence (AIECL) has attracted extensive interest
due to the significant increase in ECL response by restricting free intramolecular rotation …

Dye‐Sensitized Rare Earth Nanoparticles with Up/Down Conversion Luminescence for On‐Demand Gas Therapy of Glioblastoma Guided by NIR‐II Fluorescence …

Z Liu, B Yun, Y Han, Z Jiang, H Zhu… - Advanced Healthcare …, 2022 - Wiley Online Library
As the primary malignant tumor in the brain, glioblastoma exhibits a high mortality due to the
challenges for complete treatment by conventional therapeutic methods. It is of great …

[HTML][HTML] A randomized placebo-controlled PET study of ketamine´s effect on serotonin1B receptor binding in patients with SSRI-resistant depression

M Tiger, ER Veldman, CJ Ekman, C Halldin… - Translational …, 2020 - nature.com
The glutamate N-methyl-d-aspartate receptor antagonist ketamine has a rapid
antidepressant effect. Despite large research efforts, ketamine's mechanism of action in …

[HTML][HTML] Striatal dopamine supports reward expectation and learning: a simultaneous PET/fMRI study

FJ Calabro, DF Montez, B Larsen, CM Laymon… - NeuroImage, 2023 - Elsevier
Converging evidence from both human neuroimaging and animal studies has supported a
model of mesolimbic processing underlying reward learning behaviors, based on the …

[HTML][HTML] In silico assessment of electrophysiological neuronal recordings mediated by magnetoelectric nanoparticles

I Bok, I Haber, X Qu, A Hai - Scientific Reports, 2022 - nature.com
Magnetoelectric materials hold untapped potential to revolutionize biomedical technologies.
Sensing of biophysical processes in the brain is a particularly attractive application, with the …