Several noninvasive methods, such as high-density EEG or magnetoencephalography, are
currently used to delineate the epileptogenic zone (EZ) during the presurgical evaluation of …

Electroencephalography (EEG) has been the primary diagnostic tool in clinical epilepsy for
nearly a century. Its review is performed using qualitative clinical methods that have …

High-frequency oscillations (HFOs) encompass ripples (80 Hz–200 Hz) and fast ripples (200
Hz–600 Hz), serving as a promising biomarker for localizing the epileptogenic zone in …

Objective We hypothesized that spatio-temporal dynamics of interictal spikes reflect the
extent and stability of epileptic sources and determine surgical outcome. Methods We …

Stereo-electroencephalography (SEEG) is the gold standard to delineate surgical targets in
focal drug-resistant epilepsy. SEEG uses electrodes placed directly into the brain to identify …

Objective To confirm and investigate why pathological high‐frequency oscillations (pHFOs),
including ripples (80–200 Hz) and fast ripples (200–600 Hz), are generated during the UP …

In recent decades, a significant body of evidence based on invasive clinical research has
showed that high-frequency oscillations (HFOs) are a promising biomarker for localization of …

Understanding the neuronal basis of epileptic activity is a major challenge in neurology.
Cellular integration into larger scale networks is all the more challenging. In the local field …

In drug-resistant focal epilepsy, interictal high-frequency oscillations (HFOs) recorded from
intracranial EEG (iEEG) may provide clinical information for delineating epileptogenic brain …

In medication-resistant epilepsy, the objective of epilepsy surgery is to render a patient
seizure 3 free with a resection/ablation that is as small as possible to minimize morbidity …