The Role of High-Frequency Oscillation Networks in Managing Pharmacoresistant Epilepsy

SA Weiss, RJ Staba - Pharmacoresistance in Epilepsy: From Genes and …, 2023 - Springer
Persons with pharmacoresistant epilepsy have a higher risk of mortality than those with
controlled seizures. Seizure control can be achieved with surgical removal or electrical …

[HTML][HTML] A multi-head self-attention deep learning approach for detection and recommendation of neuromagnetic high frequency oscillations in epilepsy

X Zhao, X Peng, K Niu, H Li, L He, F Yang… - Frontiers in …, 2022 - frontiersin.org
Magnetoencephalography is a noninvasive neuromagnetic technology to record epileptic
activities for the pre-operative localization of epileptogenic zones, which has received …

Has recording of seizures become obsolete?

J Gotman - Revue Neurologique, 2023 - Elsevier
Some patients with medically intractable epilepsy are considered for surgical treatment. In
some surgical candidates, the investigation includes the placement of intracerebral …

Interictal sleep recordings during presurgical evaluation: Bidirectional perspectives on sleep related network functioning

V Dinkelacker, J El Helou, B Frauscher - Revue Neurologique, 2022 - Elsevier
Sleep recordings are an integral part of presurgical evaluation in drug-resistant focal
epilepsy. Physiological network functioning is substantially different between wakefulness …

[HTML][HTML] Interictal MEG abnormalities to guide intracranial electrode implantation and predict surgical outcome

T Owen, V Janiukstyte, GR Hall, FA Chowdhury… - Arxiv, 2023 - ncbi.nlm.nih.gov
Intracranial EEG (iEEG) is the gold standard technique for epileptogenic zone (EZ)
localisation, but requires a preconceived hypothesis of the location of the epileptogenic …

Discovering Neurophysiological Characteristics of Pathological High-Frequency Oscillations in Epilepsy with an Explainable Deep Generative Model

Y Zhang, A Daida, L Liu, N Kuroda, Y Ding, S Oana… - medRxiv, 2024 - medrxiv.org
Interictal high-frequency oscillation (HFO) is a promising biomarker of the epileptogenic
zone (EZ). However, objective definitions to distinguish between pathological and …

Simulated resections and RNS placement can optimize post-operative seizure outcomes when guided by fast ripple networks.

SA Weiss, MR Sperling, J Engel, A Liu, I Fried, C Wu… - medRxiv, 2024 - medrxiv.org
In medication-resistant epilepsy, the goal of epilepsy surgery is to make a patient seizure
free with a resection/ablation that is as small as possible to minimize morbidity. The standard …

Interictal waking and sleep electrophysiological properties of the thalamus in focal epilepsies

T Biagioni, M Fratello, E Garnier, S Lagarde, R Carron… - medRxiv, 2024 - medrxiv.org
Introduction: Addressing drug-resistant epilepsy poses a significant clinical hurdle,
particularly when conventional resective surgery is not feasible. Deep brain stimulation …

Recruitment of interictal-and ictal-like discharges in posterior piriform cortex by delta-rate (1–4 Hz) focal bursts in anterior piriform cortex in vivo

LB Haberly - Epilepsy Research, 2022 - Elsevier
The development and propagation of seizure-related activity was studied in piriform cortex
(PC) and areas in the medial temporal lobe to which it projects. In the urethane anesthetized …

[PDF][PDF] BRAIN COMMUNICATIONS

SA Weiss, I Fried, J Engel Jr, MR Sperling, RKS Wong… - 2023 - researchgate.net
Spontaneous inter-ictal epileptiform spikes (ie spikes) were first recognized nearly a century
ago in extracellular recordings from animals exposed to chemoconvulsants and in the EEG …