Mesenchymal stem cells stimulate protective genetic reprogramming of injured cardiac ventricular myocytes

TB Rogers, S Pati, S Gaa, D Riley, AY Khakoo… - Journal of Molecular and …, 2011 - Elsevier
Since massive irreversible loss of cardiac myocytes occurs following myocardial injury,
injection of human mesenchymal stem cells (hMSCs) has emerged as a promising …

Quantitative evaluation of the dynamic activity of HeLa cells in different viability states using dynamic full-field optical coherence microscopy

S Park, T Nguyen, E Benoit, DL Sackett… - Biomedical Optics …, 2021 - opg.optica.org
Dynamic full-field optical coherence microscopy (DFFOCM) was used to characterize the
intracellular dynamic activities and cytoskeleton of HeLa cells in different viability states …

[HTML][HTML] Generation of functional cardiomyocytes from efficiently generated human iPSCs and a novel method of measuring contractility

S Rajasingh, J Thangavel, A Czirok, S Samanta… - PLoS …, 2015 - journals.plos.org
Human induced pluripotent stem cells (iPSCs) derived cardiomyocytes (iCMCs) would
provide an unlimited cell source for regenerative medicine and drug discoveries. The …

[HTML][HTML] Secretome of apoptotic peripheral blood cells (APOSEC) attenuates microvascular obstruction in a porcine closed chest reperfused acute myocardial …

K Hoetzenecker, A Assinger, M Lichtenauer… - Basic research in …, 2012 - Springer
Although epicardial blood flow can be restored by an early intervention in most cases, a lack
of adequate reperfusion at the microvascular level is often a limiting prognostic factor of …

[HTML][HTML] Irisin enhances angiogenesis of mesenchymal stem cells to promote cardiac function in myocardial infarction via Pi3k/Akt activation

F Yang, Z Wang, B Li, Y He, F Du, S Tian… - … Journal of Stem Cells, 2021 - ncbi.nlm.nih.gov
Methods and Results In vivo, irisin-treated BMSCs (BMSCs+irisin) were transplanted into
an MI mouse model. On day 28 post-MI, blood vessel markers were detected, and cardiac …

[HTML][HTML] TMSB4 overexpression enhances the potency of marrow mesenchymal stromal cells for myocardial repair

S Tang, C Fan, CD Iroegbu, W Zhou… - Frontiers in Cell and …, 2021 - frontiersin.org
Objective The actin-sequestering proteins, thymosin beta-4 (Tβ4) and hypoxia-inducible
factor (HIF)-1α, are known to be associated with angiogenesis after myocardial infarction …

[HTML][HTML] Mesenchymal stem cell derived exosomes: a new hope for the treatment of cardiovascular disease?

CR Tsao, MF Liao, M Wang, CM Cheng… - Acta Cardiologica …, 2014 - ncbi.nlm.nih.gov
Cardiovascular disease is a major target for numerous experimental stem (progenitor) cell-
based therapies. Mesenchymal stem cells (MSCs) from different sources confer regenerative …

[HTML][HTML] Restoring ravaged heart: molecular mechanisms and clinical application of miRNA in heart regeneration

V Shah, J Shah - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Human heart development is a complex and tightly regulated process, conserving
proliferation and multipotency of embryonic cardiovascular progenitors. At terminal stage …

Molecular imaging of mesenchymal stem cell: mechanistic insight into cardiac repair after experimental myocardial infarction

J Wang, A Najjar, S Zhang, B Rabinovich… - Circulation …, 2012 - Am Heart Assoc
Background—Mesenchymal stem cells (MSCs) can differentiate into endothelial cells in
vivo. However, it is unknown if the differentiated MSCs persist in vivo and if this potential …

Antioxidant α-Mangostin Coated Woven Polycaprolactone Nanofibrous Yarn Scaffold for Cardiac Tissue Repair

A Sunil Richard, RS Verma - ACS Applied Nano Materials, 2022 - ACS Publications
Electrospun nanofibrous scaffolds are one of the most extensively used proven candidates
for scaffold-based tissue engineering applications due to their excellent nanoscale …