SARS-CoV-2 causes profound changes in the sense of smell, including total smell loss.
Although these alterations are often transient, many patients with COVID-19 exhibit olfactory …

Human immunodeficiency virus-1 (HIV-1) is known to interact with multiple host cellular
proteins during its replication in the target cell. While many of these host cellular proteins …

Viral infection of different cell types induces a unique spectrum of host defence genes,
including interferon-stimulated genes (ISGs) and genes encoding other proteins with …

Abstract Type-1 and type-3 interferons (IFNs) are important for control of viral replication;
however, less is known about the role of Type-2 IFN (IFNγ) in anti-viral immunity. We …

Exosomes can transfer genetic materials between cells. Their roles in viral infections are
beginning to be appreciated. Researches have shown that exosomes released from virus …

During routine molecular surveillance of SARS-CoV-2 performed at the National Reference
Center of Respiratory Viruses (Lyon, France)(n= 229 sequences collected February–April …

Concurrent/adjuvant cisplatin-based chemoradiotherapy is regarded as the standard of
treatment for locoregionally advanced nasopharyngeal carcinoma (NPC). However, patients …

Unbalanced protein homeostasis (proteostasis) networks are frequently linked to
tumorigenesis, making cancer cells more susceptible to treatments that target proteostasis …

Abstract Chromobox 6 (CBX6) is a subunit of Polycomb Repressive Complex 1 (PRC1) that
mediates epigenetic gene repression and acts as an oncogene or tumor suppressor in a …

Interferons (IFNs) are critical for anti-viral host defence. Type-1 and type-3 IFNs are typically
associated with early control of viral replication and promotion of inflammatory immune …