[HTML][HTML] Multi-functional BST2/tetherin against HIV-1, other viruses and LINE-1

Y Zhao, K Zhao, S Wang, J Du - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
Bone marrow stromal cell antigen 2 (BST2), also known as CD317, HM1. 24, or tetherin, is a
type II transmembrane glycoprotein. Its expression is induced by IFN-I, and it initiates host …

[HTML][HTML] Application of CRISPR/Cas genomic editing tools for HIV therapy: toward precise modifications and multilevel protection

A Maslennikova, D Mazurov - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
Although highly active antiretroviral therapy (HAART) can robustly control human
immunodeficiency virus (HIV) infection, the existence of latent HIV in a form of proviral DNA …

Retasking of canonical antiviral factors into proviral effectors

CR King, A Mehle - Current opinion in virology, 2022 - Elsevier
Highlights•Viruses can convert host antiviral factors and pathways into proviral
ones.•Components of intrinsic, innate, and adaptive immune defenses are all …

[HTML][HTML] Imaging of SARS-CoV-2 infected Vero E6 cells by helium ion microscopy

N Frese, P Schmerer, M Wortmann… - Beilstein Journal of …, 2021 - beilstein-journals.org
Helium ion microscopy (HIM) offers the opportunity to obtain direct views of biological
samples such as cellular structures, virus particles, and microbial interactions. Imaging with …

BST-2 promotes survival in circulation and pulmonary metastatic seeding of breast cancer cells

WD Mahauad-Fernandez, W Naushad, TD Panzner… - Scientific reports, 2018 - nature.com
Bone marrow stromal antigen 2 (BST-2) mediates various facets of cancer progression and
metastasis. Here, we show that BST-2 is linked to poor survival in invasive breast cancer …

New insights into the crosstalk among the interferon and inflammatory signaling pathways in response to viral infections: defense or homeostasis

J Dai, P Zhou, S Li, HJ Qiu - Viruses, 2022 - mdpi.com
Innate immunity plays critical roles in eliminating viral infections, healing an injury, and
restoring tissue homeostasis. The signaling pathways of innate immunity, including …

MicroRNA-760 inhibits cell viability and migration through down-regulating BST2 in gastric cancer

W Liu, Y Li, S Feng, Y Guan, Y Cao - The journal of biochemistry, 2020 - academic.oup.com
Gastric cancer is one of the most common types of carcinoma with a threat to global health.
MicroRNA-760 (miR-760) was significantly down-regulated in the primary tumour of patients …

BST2 promotes cell proliferation, migration and induces NF-κB activation in gastric cancer

W Liu, Y Cao, Y Guan, C Zheng - Biotechnology letters, 2018 - Springer
Objectives To investigate the functional roles of bone marrow stromal cell antigen 2 (BST2)
in gastric cancer (GC) cells and its implications in the development of GC patients. Results …

[PDF][PDF] Increased expression of interferon regulated and antiviral response genes in CD31+/CD102+ lung microvascular endothelial cells from systemic sclerosis …

S Piera-Velazquez, FA Mendoza, S Addya… - Clin Exp …, 2021 - clinexprheumatol.org
Objective Systemic sclerosis (SSc) is characterised by severe fibroproliferative
vasculopathy, fibrosis in skin and multiple internal organs, and humoral, cellular and innate …

Novel Diagnostic Biomarker BST2 Identified by Integrated Transcriptomics Promotes the Development of Endometriosis via the TNF-α/NF-κB Signaling Pathway

L Jiang, S Wang, X Xia, T Zhang, X Wang, F Zeng… - Biochemical …, 2024 - Springer
Endometriosis (EMS) is a common gynecological condition with apparent heterogeneity,
lack of diagnostic markers, and unclear pathogenesis. A series of bioinformatics methods …