La thérapie antirétrovirale (ART) a permis d'augmenter l'espérance de vie et sa qualité chez
les individus infectés par le VIH-1. Toutefois, l'inflammation chronique persiste et est …

They say,“a journey of a thousand miles begins with a single step.” A popular philosophical
metaphor aimed at motivating people that is just as true for the progression of breast cancer …

Les interférons (IFN) participent à la défense cellulaire contre les agents pathogènes viraux
et bactériens en régulant l'expression des gènes stimulés par l'IFN (ISG). Parmi ces ISG …

Background: Bone marrow stromal antigen 2 (BST-2) also known as Tetherin (CD317/HM1.
24), is a host restriction factor that blocks the release of HIV-1 virions from infected cells …

Gene function prediction has been shown to be a useful methodology for leveraging publicly-
available high-throughput datasets from open scientific repositories to identify previously …

Helium ion microscopy (HIM) offers the opportunity to obtain direct views of biological
samples such as cellular structures, virus particles, and microbial interactions. Imaging with …

The HIV-1 accessory protein Vpu enhances virus release by down-regulating cell surface
expression of the host restriction factor tetherin. To further understand the role of host …

Influenza virus continues to be an important global pathogen which poses serious health
and economic challenges. Influenza virus causes regular seasonal epidemics, intermittent …

Background: All high-risk HPV have a PDZ protein-binding motif on the carboxyl-termini of
their E6 proteins. This molecular feature is absent from low-risk HPV E6 proteins. The E6 …

Ebola virus disease (EVD) is a severe disease that affects humans and non-human
primates. The recent EVD epidemic in West Africa shows that EVD poses a severe threat to …