Patient‐derived models, including cell models (organoids and conditionally reprogrammed
cells [CRCs]) and patient‐derived xenografts, are urgently needed for both basic and …

The 5-year survival rate for patients diagnosed with distant metastatic prostate cancer in the
United States is 30.6%. Therefore, there is a great need to develop in vivo model systems to …

BACKGROUND Bone is one of the common sites of metastasis from prostate carcinoma.
Bone scintigraphy (BS) is one of the most sensitive imaging modalities currently used for …

Objective: To investigate the clinical values of magnetic resonance imaging (MRI), computed
tomography (CT) and X-ray in differential diagnosis of benign and malignant bone …

Despite recent development of next-generation androgen receptor (AR) antagonists,
metastatic castration-resistant prostate cancer (CRPC) remains incurable and requires …

Abstract Background Over 70% to 85% of men with advanced prostate cancer (PCa)
develop bone metastases characterized by severe bone pain and increased likelihood of …

Purpose In vivo optical imaging systems are essential to track disease progression and
evaluate therapeutic efficacy in animal studies. However, current approaches are limited by …

Bone metastasis (BM) is the most common malignant bone tumor and a significant cause of
morbidity and mortality for patients with cancer. Compared to other metastatic organs, bone …

摘要前列腺癌(prostate cancer, PCa) 骨转移的发生率很高, 不仅引发疼痛,
增加骨相关事件的风险, 还严重影响患者的生活质量以及缩短其生存期. 近年来, 随着对PCa …

Background Prostate cancer is a common cancer in men that annually results in more than
33 000 US deaths. Mortality from prostate cancer is largely from metastatic disease …