Mind the gap: Why many geneticists and psychological scientists have discrepant views about gene–environment interaction (G× E) research.

LE Duncan, AR Pollastri, JW Smoller - American Psychologist, 2014 - psycnet.apa.org
As our field seeks to elucidate the biopsychosocial etiologies of mental health disorders,
many traditional psychological and social science researchers have added, or plan to add …

[PDF][PDF] Recurrent CNVs disrupt three candidate genes in schizophrenia patients

T Vrijenhoek, JE Buizer-Voskamp, I van der Stelt… - The American Journal of …, 2008 - cell.com
Schizophrenia is a severe psychiatric disease with complex etiology, affecting approximately
1% of the general population. Most genetics studies so far have focused on disease …

[HTML][HTML] Advanced paternal age effects in neurodevelopmental disorders—review of potential underlying mechanisms

M Janecka, J Mill, MA Basson, A Goriely… - Translational …, 2017 - nature.com
Multiple epidemiological studies suggest a relationship between advanced paternal age
(APA) at conception and adverse neurodevelopmental outcomes in offspring, particularly …

Genetics of schizophrenia: new findings and challenges

PV Gejman, AR Sanders… - Annual review of …, 2011 - annualreviews.org
The work conducted using genome-wide approaches during the past several years has
invigorated the field, and represents the dawn of molecular genetics of schizophrenia. The …

[PDF][PDF] Microdeletions of 3q29 confer high risk for schizophrenia

JG Mulle, AF Dodd, JA McGrath, PS Wolyniec… - The American Journal of …, 2010 - cell.com
Schizophrenia (SZ) is a severe psychiatric illness that affects∼ 1% of the population and
has a strong genetic underpinning. Recently, genome-wide analysis of copy-number …

[HTML][HTML] From sperm to offspring: Assessing the heritable genetic consequences of paternal smoking and potential public health impacts

MA Beal, CL Yauk, F Marchetti - Mutation research/Reviews in mutation …, 2017 - Elsevier
Individuals who smoke generally do so with the knowledge of potential consequences to
their own health. What is rarely considered are the effects of smoking on their future children …

Rare copy number variants in tourette syndrome disrupt genes in histaminergic pathways and overlap with autism

TV Fernandez, SJ Sanders, IR Yurkiewicz… - Biological …, 2012 - Elsevier
BACKGROUND: Studies of copy number variation (CNV) have characterized loci and
molecular pathways in a range of neuropsychiatric conditions. We analyzed rare CNVs in …

Palmitoylation-dependent neurodevelopmental deficits in a mouse model of 22q11 microdeletion

J Mukai, A Dhilla, LJ Drew, KL Stark, L Cao… - Nature …, 2008 - nature.com
Abstract Individuals with 22q11. 2 microdeletions have cognitive deficits and a high risk of
developing schizophrenia. Here we provide evidence that primary hippocampal neurons …

Imaging phenotypes of major depressive disorder: genetic correlates

JB Savitz, WC Drevets - Neuroscience, 2009 - Elsevier
Imaging techniques are a potentially powerful method of identifying phenotypes that are
associated with, or are indicative of, a vulnerability to developing major depressive disorder …

High-resolution copy number variation analysis of schizophrenia in Japan

I Kushima, B Aleksic, M Nakatochi, T Shimamura… - Molecular …, 2017 - nature.com
Recent schizophrenia (SCZ) studies have reported an increased burden of de novo copy
number variants (CNVs) and identified specific high-risk CNVs, although with variable …