[HTML][HTML] Engineering precision nanoparticles for drug delivery

MJ Mitchell, MM Billingsley, RM Haley… - Nature reviews drug …, 2021 - nature.com
In recent years, the development of nanoparticles has expanded into a broad range of
clinical applications. Nanoparticles have been developed to overcome the limitations of free …

Where is nano today and where is it headed? A review of nanomedicine and the dilemma of nanotoxicology

C Domingues, A Santos, C Alvarez-Lorenzo… - ACS …, 2022 - ACS Publications
Worldwide nanotechnology development and application have fueled many scientific
advances, but technophilic expectations and technophobic demands must be …

[HTML][HTML] Polymeric particle-based therapies for acute inflammatory diseases

ER Brannon, MV Guevara, NJ Pacifici, JK Lee… - Nature Reviews …, 2022 - nature.com
Acute inflammation is essential for initiating and coordinating the body's response to injuries
and infections. However, in acute inflammatory diseases, inflammation is not resolved but …

Extraction, structure, pharmacological activities and drug carrier applications of Angelica sinensis polysaccharide

J Nai, C Zhang, H Shao, B Li, H Li, L Gao, M Dai… - International journal of …, 2021 - Elsevier
Angelica sinensis polysaccharide (ASP) is one of the main active components of Angelica
sinensis (AS) that is widely used in traditional Chinese medicine. ASP is water-soluble …

[HTML][HTML] Drug delivery systems in regenerative medicine: an updated review

A Mansour, M Romani, AB Acharya, B Rahman… - Pharmaceutics, 2023 - mdpi.com
Modern drug discovery methods led to evolving new agents with significant therapeutic
potential. However, their properties, such as solubility and administration-related …

Phenylboronic acid modification augments the lysosome escape and antitumor efficacy of a cylindrical polymer brush-based prodrug

R Wang, C Yin, C Liu, Y Sun, P Xiao, J Li… - Journal of the …, 2021 - ACS Publications
Timely lysosome escape is of paramount importance for endocytosed nanomedicines to
avoid premature degradation under the acidic and hydrolytic conditions in lysosomes …

Polysaccharides derived from Chinese medicinal herbs: A promising choice of vaccine adjuvants

X Wan, Y Yin, C Zhou, L Hou, Q Cui, X Zhang… - Carbohydrate …, 2022 - Elsevier
Adjuvants have been used in vaccines for a long time to promote the body's immune
response, reducing vaccine dosage and production costs. Although many vaccine adjuvants …

In vivo fate and intracellular trafficking of vaccine delivery systems

J Lee, D Kim, J Byun, Y Wu, J Park, YK Oh - Advanced Drug Delivery …, 2022 - Elsevier
With the pandemic of severe acute respiratory syndrome coronavirus 2, vaccine delivery
systems emerged as a core technology for global public health. Given that antigen …

Evolution of nanomedicine formulations for targeted delivery and controlled release

S Puri, M Mazza, G Roy, RM England, L Zhou… - Advanced Drug Delivery …, 2023 - Elsevier
Nanotechnology research over the past several decades has been aimed primarily at
improving the physicochemical properties of small molecules to produce druggable …

Engineering antiviral vaccines

X Zhou, X Jiang, M Qu, GE Aninwene, V Jucaud… - ACS …, 2020 - ACS Publications
Despite the vital role of vaccines in fighting viral pathogens, effective vaccines are still
unavailable for many infectious diseases. The importance of vaccines cannot be overstated …