Introduction: Cancer immunotherapy is a fast-growing field that has achieved tremendous
progress in recent years. It is one of the most potent tools that can activate the immune …

Natural killer T (NKT) cells, a small population of T cells, are capable of influencing a wide
range of the immune cells, including T cells, B cells, dendritic cells and macrophages. In the …

In recent years, nanovaccine based on nanomaterials emerging as an advanced
nanotechnology has drawn more attention for accurately enhancing anti-tumor …

Infection by SARS-CoV-2 virus often induces the dysregulation of immune responses, tissue
damage, and blood clotting. Engineered biomaterials from the nano-to the macroscale can …

Background It remains a huge challenge to recover the intestine immune function for the
treatment of intestinal mucosal damage from chemotherapy with cyclophosphamide (CY) …

Pickering emulsion has great potential as a vaccine adjuvant due to its unique advantages
such as its high antigen loading efficiency, great stability, etc. Among several adjuvants on …

Oral vaccines are a safe and convenient alternative to injected vaccines and have great
potential to prevent major infectious diseases. However, the harsh gastrointestinal (GI) …

Individualized immunotherapy has attracted great attention due to its high specificity,
effectiveness, and safety. We used an exogenous antigen to label tumor cells with MHC I …

Efficient therapeuic proteins' delivery into mammalian cells and subcellular transport (eg,
fast escape from endolysosomes into cytoplasm) are two key biological barriers that need to …

Cationic PLGA nanoparticles-based delivery systems have been extensively employed as
nanocarriers for drugs and antigens in recent years. Herein, we investigated the effects of …