Polyphenols and human health: The role of bioavailability

C Di Lorenzo, F Colombo, S Biella, C Stockley… - Nutrients, 2021 - mdpi.com
Polyphenols are a group of phytochemicals with potential health-promoting effects. They are
classified as flavonoid (flavonols, flavanols, flavones, flavanones, isoflavones, and …

State of the art of anthocyanins: Antioxidant activity, sources, bioavailability, and therapeutic effect in human health

N Tena, J Martín, AG Asuero - Antioxidants, 2020 - mdpi.com
The antioxidant activity of anthocyanins in food is well known. Numerous antioxidant assays
have been proposed to measure the capacity of anthocyanins to prevent the oxidation …

Fruits, vegetables, and health: A comprehensive narrative, umbrella review of the science and recommendations for enhanced public policy to improve intake

TC Wallace, RL Bailey, JB Blumberg… - Critical reviews in …, 2020 - Taylor & Francis
Fruit and vegetables (F&V) have been a cornerstone of healthy dietary recommendations;
the 2015–2020 US Dietary Guidelines for Americans recommend that F&V constitute one …

[HTML][HTML] Recent research on the health benefits of blueberries and their anthocyanins

W Kalt, A Cassidy, LR Howard, R Krikorian, AJ Stull… - Advances in …, 2020 - Elsevier
Awareness of the human health benefits of blueberries is underpinned by a growing body of
positive scientific evidence from human observational and clinical research, plus …

Systematic review on polyphenol intake and health outcomes: is there sufficient evidence to define a health-promoting polyphenol-rich dietary pattern?

C Del Bo', S Bernardi, M Marino, M Porrini, M Tucci… - Nutrients, 2019 - mdpi.com
Growing evidence support association between polyphenol intake and reduced risk for
chronic diseases, even if there is a broad debate about the effective amount of polyphenols …

Flavonoids and their anti-diabetic effects: Cellular mechanisms and effects to improve blood sugar levels

RK Al-Ishaq, M Abotaleb, P Kubatka, K Kajo… - Biomolecules, 2019 - mdpi.com
Diabetes mellitus (DM) is a prevailing global health metabolic disorder, with an alarming
incidence rate and a huge burden on health care providers. DM is characterized by the …

Improvement strategies for the oral bioavailability of poorly water-soluble flavonoids: An overview

J Zhao, J Yang, Y Xie - International journal of pharmaceutics, 2019 - Elsevier
Although flavonoid compounds have various pharmacological applications, they generally
exhibit low oral bioavailability due to their poor aqueous solubility. To address this problem …

[HTML][HTML] The role of metabolism (and the microbiome) in defining the clinical efficacy of dietary flavonoids

A Cassidy, AM Minihane - The American journal of clinical nutrition, 2017 - Elsevier
At a population level, there is growing evidence of the beneficial effects of dietary flavonoids
on health. However, there is extensive heterogeneity in the response to increased intake …

Polyphenols and glycemic control

Y Kim, JB Keogh, PM Clifton - Nutrients, 2016 - mdpi.com
Growing evidence from animal studies supports the anti-diabetic properties of some dietary
polyphenols, suggesting that dietary polyphenols could be one dietary therapy for the …

Dietary polyphenols and type 2 diabetes: Human Study and Clinical Trial

H Cao, J Ou, L Chen, Y Zhang… - Critical reviews in …, 2019 - Taylor & Francis
Significant evidence from epidemiological investigations showed that dietary polyphenols
might manage and prevent type 2 diabetes (T2D). This review summarizes human studies …