Anti-diabetic and anti-obesity: Efficacy evaluation and exploitation of polyphenols in fruits and vegetables

L Chen, Y Pu, Y Xu, X He, J Cao, Y Ma… - Food Research …, 2022 - Elsevier
Polyphenols are a group of secondary plant metabolites widely present in diets and have
antagonistic effects on some chronic metabolic diseases, like type 2 diabetes (T2D) and …

[HTML][HTML] Hypoglycemic and hypolipidemic effects of blueberry anthocyanins by AMPK activation: In vitro and in vivo studies

DD Herrera-Balandrano, Z Chai, RP Hutabarat, T Beta… - Redox biology, 2021 - Elsevier
Blueberries are rich in bioactive anthocyanins, with a high level of malvidin, which is
associated with antioxidant benefits that contribute to reducing the risk of diabetes. The …

Evaluation of a flavonoids library for inhibition of pancreatic α-amylase towards a structure–activity relationship

C Proença, M Freitas, D Ribeiro, SM Tomé… - Journal of enzyme …, 2019 - Taylor & Francis
Abstract α-Amylase has been considered an important therapeutic target for the
management of type 2 diabetes mellitus (T2DM), decreasing postprandial hyperglycaemia …

Citrus flavonoids and lipid metabolism

JM Assini, EE Mulvihill, MW Huff - Current opinion in lipidology, 2013 - journals.lww.com
These recent studies suggest an important role of citrus flavonoids in the treatment of
dyslipidemia, insulin resistance, hepatic steatosis, obesity and atherosclerosis. The …

Dietary intake and major food sources of polyphenols in a Spanish population at high cardiovascular risk: the PREDIMED study

A Tresserra-Rimbau, A Medina-Remón… - Nutrition, Metabolism …, 2013 - Elsevier
Background and aims Epidemiological data have shown an inverse association between
the consumption of polyphenol-rich foods and the risk of cardiovascular disease or overall …

Trending cardiovascular nutrition controversies

AM Freeman, PB Morris, N Barnard… - Journal of the American …, 2017 - jacc.org
The potential cardiovascular benefits of several trending foods and dietary patterns are still
incompletely understood, and nutritional science continues to evolve. However, in the …

[HTML][HTML] Intakes of anthocyanins and flavones are associated with biomarkers of insulin resistance and inflammation in women

A Jennings, AA Welch, T Spector, A Macgregor… - The Journal of …, 2014 - Elsevier
Although laboratory data suggest that several flavonoid subclasses are involved in glucose
metabolism, limited clinical and epidemiologic data are available. The current study …

[HTML][HTML] Higher dietary anthocyanin and flavonol intakes are associated with anti-inflammatory effects in a population of US adults

A Cassidy, G Rogers, JJ Peterson, JT Dwyer… - The American journal of …, 2015 - Elsevier
Background: Although growing evidence from trials and population-based studies has
supported a protective role for flavonoids in relation to risk of certain chronic diseases, the …

Flavonoid intake in European adults (18 to 64 years)

A Vogiatzoglou, AA Mulligan, MAH Lentjes, RN Luben… - PloS one, 2015 - journals.plos.org
Background Flavonoids are a group of phenolic secondary plant metabolites that are
ubiquitous in plant-based diets. Data from anthropological, observational and intervention …

[HTML][HTML] Blueberry anthocyanin intake attenuates the postprandial cardiometabolic effect of an energy-dense food challenge: Results from a double blind, randomized …

PJ Curtis, L Berends, V van der Velpen, A Jennings… - Clinical Nutrition, 2022 - Elsevier
Background & aims Whilst the cardioprotective effects of blueberry intake have been shown
in prospective studies and short-term randomized controlled trials (RCTs), it is unknown …