Very low levels of circulating monoclonal B‐cell subpopulations can now be detected in
apparently healthy individuals using flow cytometry. We propose the term 'monoclonal B‐cell …

PURPOSE To review recent advances in the pathogenesis, biology, diagnosis, and
management of chronic lymphocytic leukemia (CLL). DESIGN A literature search restricted …

Purpose The diagnosis of monoclonal B-cell lymphocytosis (MBL) is used to characterize
patients with a circulating population of clonal B cells, a total B-cell count of less than 5× …

Background Among all hematologic malignancies, B‐cell chronic lymphocytic leukemia
(BCLL) has the highest familial clustering (three‐to sevenfold increase), strongly suggesting …

In an ongoing study, families with two or more living cases of B-CLL in first-degree relatives
have been recruited through physician and self-referral. Since 1967, 28 kindreds with 73 …

Monoclonal B‐cell lymphocytosis (MBL) has been the subject of more intensive investigation
for the last 10 years. The increased presence of MBL in unaffected, first‐degree relatives …

Monoclonal B-cell lymphocytosis (MBL) is a clonal lymphoproliferation with the
immunophenotype of chronic lymphocytic leukemia (CLL) but a B-lymphocyte count of less …

Inherited susceptibility to chronic lymphocytic leukemia (CLL) has been recognized for
decades. Approximately 10% of individuals with CLL report a family history of CLL or a …

Background Monoclonal B-cell lymphocytosis (MBL) is an asymptomatic precursor condition
for chronic lymphocytic leukemia (CLL). It is defined by the presence of small clones of …

Monoclonal B-cell lymphocytosis (MBL) is an asymptomatic hematologic condition defined
by the presence of a small (< 5 x 10 9/L) clonal B-cell population in the peripheral blood in …