The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Decades of research advances have established a central role for endogenous opioid
systems in regulating reward processing, mood, motivation, learning and memory …

Chronic exposure to addictive drugs in substance use disorders and stressors in mood
disorders render the brain more vulnerable to inflammation. Inflammation in the brain, or …

During the last decade, substance use disorders (SUDs) have been increasingly recognized
as neuroinflammation-related brain diseases. Various types of abused drugs (cocaine …

Stress and substance use disorders remain two of the most highly prevalent psychiatric
conditions and are often comorbid. While individually these conditions have a debilitating …

Environmental enrichment consisting of social peers and novel objects is known to alter
neurobiological functioning and have an influence on the behavioral effects of drugs of …

Substance use disorders are a group of diseases that are associated with social,
professional, and family impairment and that represent a high socio-economic impact on the …

Substance use in adolescence is a known risk factor for the development of neuropsychiatric
and substance use disorders in adulthood. This is in part due to the fact that critical aspects …

Human immunodeficiency virus (HIV) remains a persistent public health concern throughout
the world. Substance use disorders (SUDs) are a common comorbidity that can worsen …

The lipid-derived messenger oleoylethanolamide (OEA) has been involved in multiple
physiological functions including metabolism and the immune response. More recently, OEA …