During the last decade infections caused by MDR Gram-negative bacteria (GNB) have
become increasingly prevalent. Because of their high morbidity and mortality rates, these …

Antibiotics are the current standard-of-care treatment for uncomplicated urinary tract
infections (uUTIs). However, increasing rates of bacterial antibiotic resistance necessitate …

Purpose Carbapenems are considered the most efficient antibiotic used in the treatment of
nosocomial infections. Carbapenem-resistant Gram-negative rods are becoming a serious …

The emergence of multidrug resistance in pathogenic bacteria limits the utilization of
available antibiotics. The development of alternate options to treat infectious diseases is the …

The prevalence of carbapenemase-producing Enterobacteriaceae (CPE) has increased
during the past 10 years. Its detection is frequently difficult, because they do not always …

Abstract Ceftazidime/avibactam (CAZ/AVI), a combination of ceftazidime and a novel β‐
lactamase inhibitor (avibactam) that has been approved by the US Food and Drug …

Background Bloodstream infections (BSI) are associated with high morbidity and mortality.
This scenario worsens with the emergence of drug-resistant pathogens, resulting in …

The objective of this study was to investigate predisposing factors and outcomes of infective
endocarditis (IE) caused by non-HACEK Gram-negative bacilli (GNB) in a contemporary …

Background: Vancomycin-resistant enterococci (VRE) are among the most common
healthcare associated multidrug-resistant organisms. Purpose of the article was to review …

Shikonin (SKN), a highly liposoluble naphthoquinone pigment isolated from the roots of
Lithospermum erythrorhizon, is known to exert antibacterial, wound‐healing, anti …