Association between metabolites in tryptophan-kynurenine pathway and inflammatory bowel disease: A two-sample Mendelian randomization
F Yu, Y Du, C Li, H Zhang, W Lai, S Li, Z Ye, W Fu… - Scientific Reports, 2024 - nature.com
Previous observational studies have suggested an association between tryptophan (TRP)–
kynurenine (KYN) pathway and inflammatory bowel disease (IBD). However, whether there …
kynurenine (KYN) pathway and inflammatory bowel disease (IBD). However, whether there …
Dexamethasone-Loaded Lipid Calcium Phosphate Nanoparticles Treat Experimental Colitis by Regulating Macrophage Polarization in Inflammatory Sites
K Dong, Y Zhang, HR Ji, ZL Guan… - International journal …, 2024 - Taylor & Francis
Background The M1/M2 polarization of intestinal macrophages exerts an essential function
in the pathogenesis of ulcerative colitis (UC), which can be adjusted to alleviate the UC …
in the pathogenesis of ulcerative colitis (UC), which can be adjusted to alleviate the UC …
Single-cell RNA profiling reveals classification and characteristics of mononuclear phagocytes in colorectal cancer
T Ji, H Fu, L Wang, J Chen, S Tian, G Wang… - Plos …, 2024 - journals.plos.org
Colorectal cancer (CRC) is a major cause of cancer mortality and a serious health problem
worldwide. Mononuclear phagocytes are the main immune cells in the tumor …
worldwide. Mononuclear phagocytes are the main immune cells in the tumor …
The Role of TAMs in the Regulation of Tumor Cell Resistance to Chemotherapy
R McWhorter, B Bonavida - Critical Reviews™ in Oncogenesis - dl.begellhouse.com
Tumor-associated macrophages (TAMs) are the predominant cell infiltrate in the
immunosuppressive tumor microenvironment (TME). TAMs are central to fostering pro …
immunosuppressive tumor microenvironment (TME). TAMs are central to fostering pro …