Importance Multisystem inflammatory syndrome in adults (MIS-A) has not been well
described. Improved diagnosis and treatment of MIS-A might mitigate COVID-19 morbidity …

COVID-19 is primarily a respiratory disease but up to two thirds of hospitalised patients show
evidence of central nervous system (CNS) damage, predominantly ischaemic, in some …

COVID-19 shares the feature of autoantibody production with systemic autoimmune
diseases. In order to understand the role of these immune globulins in the pathogenesis of …

Objectives To describe the clinical characteristics, laboratory results, imaging findings, and
in-hospital outcomes of COVID-19 patients admitted to Brazilian hospitals. Methods A cohort …

Background Excess visceral fat (VF) or high body mass index (BMI) is risk factors for severe
COVID-19. The receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Cyclic guanosine monophosphate (cGMP), an important intracellular second messenger,
mediates cellular functional responses in all vital organs. Phosphodiesterase 5 (PDE5) is …

It has been a year since the coronavirus disease 2019 (COVID-19) was declared pandemic
and wreak havoc worldwide. Despite meticulous research has been done in this period …

Background A local increase in angiotensin 2 after inactivation of angiotensin-converting
enzyme 2 by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may induce a …

COVID-19 and the renin-angiotensin system (RAS) are linked by angiotensin-converting
enzyme 2 (ACE2), a key enzyme in RAS that has been validated as a SARS-CoV-2 receptor …

Objective: The aim of this review was to summarize the most common extrapulmonary
manifestations in pediatric patients with COVID-19, as well as to discuss clinical …