Cancer immunotherapy critically relies on the efficient presentation of tumor antigens to T-
cells to elicit a potent anti-tumor immune response aimed at life-long protection against …

Drug encapsulated liposomes and monoclonal antibodies (Mabs) are two distinctively
different classes of therapeutics, but both aim to become the ultimate “magic bullet”. While …

Immunotherapy is a promising treatment modality for cancer as it can promote specific and
durable anti-cancer responses. However, limitations to current approaches remain …

Immunotherapy involves the therapeutic alteration of the patient's immune system to identify,
target, and eliminate cancer cells. Dendritic cells, macrophages, myeloid-derived …

T cell-based adoptive cell therapy (ACT) has emerged as a promising treatment for various
diseases, particularly cancers. Unlike other immunotherapy modalities, ACT involves directly …

Although adoptive transfer of therapeutic cells to cancer patients is demonstrated with great
success and fortunately approved for the treatment of leukemia and B‐cell lymphoma …

The immune system protects the body against a wide range of infectious diseases and
cancer by leveraging the efficiency of immune cells and lymphoid organs. Over the past …

We propose an ex vivo T cell expansion system that mimics natural antigen-presenting cells
(APCs) for adoptive cell therapy (ACT). Microfiber scaffolds coated with dendritic cell (DC) …

The metastases of malignant tumors develop through a cascade of events. The
establishment of a pre-metastatic micro-environment is initiated by communication between …

Cancer immunotherapy has recently burst onto the center stage of cancer treatment and
research. T lymphocyte adoptive cellular transfer (ACT), a form of cancer immunotherapy …