Low-dose effects of hormones and endocrine disruptors

LN Vandenberg - Vitamins & hormones, 2014 - Elsevier
Endogenous hormones have effects on tissue morphology, cell physiology, and behaviors at
low doses. In fact, hormones are known to circulate in the part-per-trillion and part-per-billion …

[HTML][HTML] Cumulative risk assessment of five phthalates in European children and adolescents

R Lange, N Vogel, P Schmidt, A Gerofke… - International Journal of …, 2022 - Elsevier
Abstract The European Human Biomonitoring Initiative (HBM4EU) assessed human
biomonitoring data on phthalates in children and adolescents, that were sampled between …

Exposure to indoor endocrine‐disrupting chemicals and childhood asthma and obesity

I Paciência, J Cavaleiro Rufo, D Silva, C Martins… - Allergy, 2019 - Wiley Online Library
Background Indoor air contaminants may act as endocrine‐disrupting chemicals (EDCs).
However, to what extent these contaminants affect health is poorly known. We aimed to …

Toxic effects of the mixture of phthalates and bisphenol a—subacute oral toxicity study in wistar rats

K Baralić, A Buha Djordjevic, K Živančević… - International journal of …, 2020 - mdpi.com
Phthalates and bisphenol A, classified as endocrine disruptors, have weak estrogenic, anti-
androgenic properties, and affect thyroid hormone regulation. The aim of this study on male …

[HTML][HTML] Adipocytes under assault: environmental disruption of adipose physiology

SM Regnier, RM Sargis - Biochimica et Biophysica Acta (BBA)-Molecular …, 2014 - Elsevier
The burgeoning obesity epidemic has placed enormous strains on individual and societal
health mandating a careful search for pathogenic factors, including the contributions made …

Why endocrine disrupting chemicals (EDCs) challenge traditional risk assessment and how to respond

VF Fuhrman, A Tal, S Arnon - Journal of hazardous materials, 2015 - Elsevier
Endocrine disrupting compounds (EDCs) are a diverse group of “chemicals of emerging
concern” which have attracted much interest from the research community since the 1990s …

Genital anomalies in boys and the environment

KM Main, NE Skakkebaek, HE Virtanen… - Best Practice & Research …, 2010 - Elsevier
The prevalence of male reproductive disorders, such as testicular cancer and impaired
semen quality, is increasing in many, albeit not all, countries. These disorders are …

Prenatal environmental risk factors for genital malformations in a population of 1442 French male newborns: a nested case–control study

L Gaspari, F Paris, C Jandel, N Kalfa… - Human …, 2011 - academic.oup.com
BACKGROUND Over the past decades, an increasing trend in male external genital
malformations such as cryptorchidism and hypospadias has led to the suspicion that …

Environmental chemicals and thyroid function: an update

M Boas, KM Main… - Current Opinion in …, 2009 - journals.lww.com
A large variety of ubiquitous chemicals have been shown to have thyroid-disrupting
properties, and the combination of mechanistic, epidemiological and exposure studies …

Chronic dietary exposure to a low-dose mixture of genistein and vinclozolin modifies the reproductive axis, testis transcriptome, and fertility

F Eustache, F Mondon… - Environmental …, 2009 - ehp.niehs.nih.gov
Background The reproductive consequences and mechanisms of action of chronic exposure
to low-dose endocrine disruptors are poorly understood. Objective We assessed the effects …