Recommendations for the use of structural magnetic resonance imaging in the care of patients with epilepsy: a consensus report from the International League Against …

A Bernasconi, F Cendes, WH Theodore, RS Gill… - …, 2019 - Wiley Online Library
Structural magnetic resonance imaging (MRI) is of fundamental importance to the diagnosis
and treatment of epilepsy, particularly when surgery is being considered. Despite previous …

Brain imaging in the assessment for epilepsy surgery

JS Duncan, GP Winston, MJ Koepp… - The Lancet …, 2016 - thelancet.com
Brain imaging has a crucial role in the presurgical assessment of patients with epilepsy.
Structural imaging reveals most cerebral lesions underlying focal epilepsy. Advances in MRI …

Interpretable surface-based detection of focal cortical dysplasias: a Multi-centre Epilepsy Lesion Detection study

H Spitzer, M Ripart, K Whitaker, F D'Arco, K Mankad… - Brain, 2022 - academic.oup.com
One outstanding challenge for machine learning in diagnostic biomedical imaging is
algorithm interpretability. A key application is the identification of subtle epileptogenic focal …

Radiological images and machine learning: trends, perspectives, and prospects

Z Zhang, E Sejdić - Computers in biology and medicine, 2019 - Elsevier
The application of machine learning to radiological images is an increasingly active
research area that is expected to grow in the next five to ten years. Recent advances in …

Getting the best outcomes from epilepsy surgery

VN Vakharia, JS Duncan, JA Witt, CE Elger… - Annals of …, 2018 - Wiley Online Library
Neurosurgery is an underutilized treatment that can potentially cure drug‐refractory
epilepsy. Careful, multidisciplinary presurgical evaluation is vital for selecting patients and to …

Familial focal epilepsy with focal cortical dysplasia due to DEPDC5 mutations

S Baulac, S Ishida, E Marsan, C Miquel… - Annals of …, 2015 - Wiley Online Library
Objective The DEPDC5 (DEP domain‐containing protein 5) gene, encoding a repressor of
the mTORC1 signaling pathway, has recently emerged as a major gene mutated in familial …

Neuroimaging of epilepsy

F Cendes, WH Theodore, BH Brinkmann, V Sulc… - Handbook of clinical …, 2016 - Elsevier
Imaging is pivotal in the evaluation and management of patients with seizure disorders.
Elegant structural neuroimaging with magnetic resonance imaging (MRI) may assist in …

Value of 7T MRI and post‐processing in patients with nonlesional 3T MRI undergoing epilepsy presurgical evaluation

I Wang, S Oh, I Blümcke, R Coras, B Krishnan… - …, 2020 - Wiley Online Library
Abstract Objective Ultra‐high‐field 7‐Tesla (7T) magnetic resonance imaging (MRI) offers
increased signal‐to‐noise and contrast‐to‐noise ratios, which may improve visualization of …

Multicenter validation of a deep learning detection algorithm for focal cortical dysplasia

RS Gill, HM Lee, B Caldairou, SJ Hong, C Barba… - Neurology, 2021 - AAN Enterprises
Background and Objective To test the hypothesis that a multicenter-validated computer deep
learning algorithm detects MRI-negative focal cortical dysplasia (FCD). Methods We used …

Atlas of lesion locations and postsurgical seizure freedom in focal cortical dysplasia: A MELD study

K Wagstyl, K Whitaker, A Raznahan, J Seidlitz… - …, 2022 - Wiley Online Library
Objective Drug‐resistant focal epilepsy is often caused by focal cortical dysplasias (FCDs).
The distribution of these lesions across the cerebral cortex and the impact of lesion location …