Functional image-guided radiotherapy planning for normal lung avoidance

RH Ireland, BA Tahir, JM Wild, CE Lee, MQ Hatton - Clinical Oncology, 2016 - Elsevier
For patients with lung cancer undergoing curative intent radiotherapy, functional lung
imaging can be incorporated into treatment planning to modify the dose distribution within …

Functional imaging for assessing regional lung ventilation in preclinical and clinical research

D Karmali, M Sowho, S Bose, J Pearce… - Frontiers in …, 2023 - frontiersin.org
Dynamic heterogeneity in lung ventilation is an important measure of pulmonary function
and may be characteristic of early pulmonary disease. While standard indices like …

The VAMPIRE challenge: a multi‐institutional validation study of CT ventilation imaging

J Kipritidis, BA Tahir, G Cazoulat, MS Hofman… - Medical …, 2019 - Wiley Online Library
Purpose CT ventilation imaging (CTVI) is being used to achieve functional avoidance lung
cancer radiation therapy in three clinical trials (NCT02528942, NCT02308709 …

Using hyperpolarized 129Xe MRI to quantify the pulmonary ventilation distribution

M He, B Driehuys, LG Que, YCT Huang - Academic radiology, 2016 - Elsevier
Rationale and Objectives Ventilation heterogeneity is impossible to detect with spirometry.
Alternatively, pulmonary ventilation can be imaged three-dimensionally using inhaled 129 …

Validating and improving CT ventilation imaging by correlating with ventilation 4D‐PET/CT using 68Ga‐labeled nanoparticles

J Kipritidis, S Siva, MS Hofman, J Callahan… - Medical …, 2014 - Wiley Online Library
Purpose: CT ventilation imaging is a novel functional lung imaging modality based on
deformable image registration. The authors present the first validation study of CT ventilation …

4D CT lung ventilation images are affected by the 4D CT sorting method

T Yamamoto, S Kabus, C Lorenz, E Johnston… - Medical …, 2013 - Wiley Online Library
Purpose: Four‐dimensional (4D) computed tomography (CT) ventilation imaging is a novel
promising technique for lung functional imaging. The current standard 4D CT technique …

Imaging the injured lung: mechanisms of action and clinical use

M Cereda, Y Xin, A Goffi, J Herrmann, DW Kaczka… - …, 2019 - pubs.asahq.org
Acute respiratory distress syndrome (ARDS) consists of acute hypoxemic respiratory failure
characterized by massive and heterogeneously distributed loss of lung aeration caused by …

Validating the distribution of specific ventilation in healthy humans measured using proton MR imaging

RC Sá, AK Asadi, RJ Theilmann… - Journal of Applied …, 2014 - journals.physiology.org
Specific ventilation imaging (SVI) uses proton MRI to quantitatively map the distribution of
specific ventilation (SV) in the human lung, using inhaled oxygen as a contrast agent. To …

Respiratory dynamics in phonation and breathing—A real-time MRI study

L Traser, AC Özen, F Burk, M Burdumy, M Bock… - Respiratory physiology …, 2017 - Elsevier
The respiratory system is a central part of voice production, but for phonation neither the
underlying functional relations between diaphragm (DPH) and rib cage (RC), nor differences …

Assessment of pulmonary structure–function relationships in young children and adolescents with cystic fibrosis by multivolume proton‐MRI and CT

F Pennati, DJ Roach, JP Clancy… - Journal of Magnetic …, 2018 - Wiley Online Library
Background Lung disease is the most frequent cause of morbidity and mortality in patients
with cystic fibrosis (CF), and there is a shortage of sensitive biomarkers able to regionally …